Στην βιολογία, το περιβάλλον μπορεί να καθοριστεί σαν ενα σύνολο κλιματικών, βιοτικών, κοινωνικών και εδαφικών παραγόντων που δρουν σε έναν οργανισμό και καθορίζουν την ανάπτυξη και την επιβίωση του. Έτσι, περιλαμβάνει οτιδήποτε μπορεί να επηρεάσει άμεσα τον μεταβολισμό ή τη συμπεριφορά των ζωντανών οργανισμών ή ειδών, όπως το φως, ο αέρας, το νερό, το έδαφος και άλλοι παράγοντες. Δείτε επίσης το άρθρο για το φυσικό περιβάλλον και τη φυσική επιλογή.
Στην αρχιτεκτονική, την εργονομία και την ασφάλεια στην εργασία, περιβάλλον είναι το σύνολο των χαρακτηριστικών ενός δωματίου ή κτιρίου που επηρεάζουν την ποιότητα ζωής και την αποδοτικότητα, περιλαμβανομένων των διαστάσεων και της διαρρύθμισης των χώρων διαβίωσης και της επίπλωσης, του φωτισμού, του αερισμού, της θερμοκρασίας, του θορύβου κλπ. Επίσης μπορεί να αναφέρεται στο σύνολο των δομικών κατασκευών. Δείτε επίσης το άρθρο για το δομημένο περιβάλλον.
Στην ψυχολογία, περιβαλλοντισμός είναι η θεωρία ότι το περιβάλλον (με τη γενική και κοινωνική έννοια) παίζει μεγαλύτερο ρόλο από την κληρονομικότητα καθορίζοντας την ανάπτυξη ενός ατόμου. Συγκεκριμένα, το περιβάλλον είναι ένας σημαντικός παράγοντας πολλών ψυχολογικών θεωριών.
Στην τέχνη, το περιβάλλον αποτελεί κινητήριο μοχλό και μούσα εμπνέοντας τους ζωγράφους ή τους ποιητές. Σε όλες τις μορφές της Τέχνης αποτελεί έμπνευση και οι Καλές Τέχνες φανερώνουν την επιρροή οπού άσκησε σε όλους τους καλλιτέχνες με όποιο είδος Τέχνης κι αν ασχολούνται. Ο άνθρωπος μέσα στο περιβάλλον δημιουργεί Μουσική, Ζωγραφική, Ποίηση, Γλυπτική, χορό, τραγούδι, θέατρο, αλλά και όλες οι μορφές τέχνης έχουν άμεση έμπνευση από το περιβάλλον.

Παρασκευή 19 Ιουλίου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


JAMA Otolaryngology
Author Interview: Tinnitus Retraining Therapy vs Standard of Care and Tinnitus-Related Quality of LifeVIEWPOINTThe Search for and Conduct of the Elusive Phase 3 Randomized Clinical Trial: Snipe Hunting With the MilitaryCraig Formby, PhD; Roberta W. Scherer, PhDInvited Commentary: Role of the US Department of Defense Hearing Center of Excellence in Studying the Treatment of Tinnitus; Tanisha L. Hammill, PhD; Carlos R. Esquivel, MDORIGINAL INVESTIGATIONEffect of Tinnitus Retraining Therapy vs Standard...
Αλέξανδρος Γ. Σφακιανάκης
4m
MASP-1 of the complement system alters fibrinolytic behaviour of blood clots Publication date: October...
MASP-1 of the complement system alters fibrinolytic behaviour of blood clotsPublication date: October 2019Source: Molecular Immunology, Volume 114Author(s): Lorenz Jenny, Danilo Noser, Julie Brogaard Larsen, József Dobó, Péter Gál, Gábor Pál, Verena SchroederAbstractBackgroundThe lectin pathway serine protease mannan-binding lectin-associated serine protease 1 (MASP-1) has been demonstrated to be a major link between complement and coagulation, yet little is known about its interactions with the...
Αλέξανδρος Γ. Σφακιανάκης
6m
The Early–Middle Ordovician graptolite genus Azygograptus in South China: New material and paleogeographic...
The Early–Middle Ordovician graptolite genus Azygograptus in South China: New material and paleogeographic implicationsPublication date: 1 November 2019Source: Palaeogeography, Palaeoclimatology, Palaeoecology, Volume 533Author(s): Wenhui Wang, Linna Zhang, Hao Liu, Xin Deng, Jingqiang TanAbstractThis study presents a new analysis of three species of the Ordovician graptolite genus Azygograptus Nicholson & Lapworth from the Wenxiakou section in the Zhongxiang area of Hubei Province. The paleogeographic...
Αλέξανδρος Γ. Σφακιανάκης
7m
Direct evidence for agricultural intensification during the first two millennia AD in northeast Burkina...
Direct evidence for agricultural intensification during the first two millennia AD in northeast Burkina FasoPublication date: August 2019Source: Journal of Archaeological Science, Volume 108Author(s): Amy K. Styring, Alexa Höhn, Veerle Linseele, Katharina NeumannAbstractArchaeobotanical evidence from archaeological sites in northeast Burkina Faso dating to the first and second millennia AD has provided a useful insight into crop cultivation and the development of the West African savanna landscape....
Αλέξανδρος Γ. Σφακιανάκης
7m
Thromboelastography testing in mice following blood collection from facial vein and cardiac puncture...
Thromboelastography testing in mice following blood collection from facial vein and cardiac punctureBlood collection is critical for mouse research studies particularly in hemostatic testing. Cardiac puncture; a standard effective method requires anesthesia and is a terminal procedure while facial vein technique allows multiple collections. Thromboelastography (TEG) is a global hemostasis test, provides a dynamic real-time picture of coagulation. However, TEG experiments in mice require large number...
Αλέξανδρος Γ. Σφακιανάκης
8m
Efficacy and Safety of Low-dose Codeine Containing Combination Analgesics for Pain: Systematic Review...
Efficacy and Safety of Low-dose Codeine Containing Combination Analgesics for Pain: Systematic Review and Meta-analysis,Objective: To investigate the efficacy and safety of combination analgesic products containing low-dose codeine (up to 30▒mg per dose) for pain. Methods: We used electronic databases to identify eligible placebo-controlled RCTs. Two authors extracted data and assessed risk of bias. Data were pooled using a random effects model with strength of evidence assessed using GRADE. The...
Αλέξανδρος Γ. Σφακιανάκης
10m
Photodermatology, Photoimmunology & Photomedicine, Volume 35, Issue 4,Pages: 199-292, July 2019...
Photodermatology, Photoimmunology & Photomedicine,Volume 35, Issue 4,Pages: 199-292,July 2019ISSUE INFORMATIONIssue InformationPages: 199-200 | First Published: 17 July 2019ORIGINAL ARTICLES Open AccessPhotoaging and actinic keratosis in Danish outdoor and indoor workersKasper Grandahl, Jonas Olsen, Kersti Brosbøl Engelund Friis, Ole Steen Mortensen, Kristina Sophie IblerPages: 201-207 | First Published: 28 January 2019Long‐term efficacy of photodynamic therapy with methyl aminolevulinate in...
Αλέξανδρος Γ. Σφακιανάκης
11m
Anaphylaxis in adolescents, Purpose of review The frequency of hospitalization for anaphylaxis has increased...
Anaphylaxis in adolescents,Purpose of review The frequency of hospitalization for anaphylaxis has increased over the last 20 years across Europe, Australia, and North America, particularly, for food and medication triggers. Adolescents show the highest risk for morbidity and fatality from food-induced anaphylaxis, yet there is little high-quality evidence addressing the reasons for this disproportionate vulnerability. Recent findings Recent data seem to suggest a possible increasing burden of food-induced...
Αλέξανδρος Γ. Σφακιανάκης
11m
Wound Repair and Regeneration, Early View, Online Version of Record before inclusion in an issue ...
Wound Repair and Regeneration,Early View,Online Version of Record before inclusion in an issueImmunomodulatory potential of Nisin A with application in wound healingMichelle V. Mouritzen PhD, Athina Andrea PhD, Katrine Qvist MSc, Steen S. Poulsen PhD, Håvard Jenssen ScDVersion of Record online: 09 July 2019Wound Repair and RegenerationAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.Non‐invasive Staging...
Αλέξανδρος Γ. Σφακιανάκης
14m
Key role of inferior turbinectomy and partial middle turbinectomy in endoscopic surgery for allergic...
Key role of inferior turbinectomy and partial middle turbinectomy in endoscopic surgery for allergic fungal sinusitis: A comparative study,Ahmad Mostafa, Wael A Alzamil, Essam Fatehy, Mohammad M GaballahJournal of Medicine in Scientific Research 2019 2(1):65-70Background Proper eradication of allergic fungal sinusitis (AFS) depends on three factors: first is proper preoperative evaluation and mapping via computed tomography and MRI. Second is the availability of adequate surgical tools in experienced...
Αλέξανδρος Γ. Σφακιανάκης
15m
Medicine in Scientific Research
The use of microplates for fixation of mandibular fractures: a systematic reviewMagdy M Zaky, Nabila A Fayed, Mohamed F Shehab, Usama S HellalJournal of Medicine in Scientific Research 2019 2(1):1-7Background Microplates have thin diameter making them less palpable, more malleable, easily applied, and adaptable to fracture site. In the past, microplates were used in midface fractures only, but we can obtain their benefits in mandibular fractures as well. Objective The aim of this systematic review...
Αλέξανδρος Γ. Σφακιανάκης
16m
Cardiovascular Medicine
A meta-analysis of impact of low-flow/low-gradient aortic stenosis on survival after transcatheter aortic valve implantationAims To determine whether low-flow/low-gradient (LF/LG) aortic stenosis affects survival after transcatheter aortic valve implantation (TAVI), we performed a meta-analysis of currently available studies. Methods MEDLINE and EMBASE were searched through January 2019 using PubMed and OVID. Observational studies comparing all-cause mortality after TAVI for patients with classical...
Αλέξανδρος Γ. Σφακιανάκης
17m
Curative effect of aqueous extract of Cyperus esculentus on flutamide-induced testicular dysfunction
 in male Wistar ratsLuqman Adepoju Hassan, Godson Emeka Anyanwu, Nto Johnson Nto, Emmanuel Nebuwa Obikili, Elizabeth Finbarrs-Bello, L Ifeanacho Ezeteonu AbirehJournal of Experimental and Clinical Anatomy 2018 17(1):13-17BACKGROUND: The health of the testis is important for a man's sexual functioning and fertility. This study investigated the effect of aqueous extract of Cyperus esculentus on flutamide-induced testicular dysfunction in male Wistar rats. MATERIALS AND METHODS: Sixteen adult male Wistar...
Αλέξανδρος Γ. Σφακιανάκης
19m
Morphological effects of chronic administration of zidovudine on the intracranial auditory relay centers...
Morphological effects of chronic administration of zidovudine on the intracranial auditory relay centers of adult Wistar ratsPatrick Sunday Igbigbi, Josiah O Adjene, Kingsley Afoke Iteire, Babatunde Samson OgunladeJournal of Experimental and Clinical Anatomy 2018 17(1):8-12BACKGROUND: Zidovudine is one of the very active antiretroviral treatments which have been effective in several combination regimens for the treatment of HIV disease. Widely accepted theories have recognized that such treatment...
Αλέξανδρος Γ. Σφακιανάκης
20m
Experimental and Clinical Anatomy
Hepatoprotective effect of methanol fruit pulp extract of Musa paradisiaca on carbon tetrachloride-induced liver toxicity in Wistar ratsMustapha Tosin Issa, Abel Nosereme Agbon, Sadiya Ufeli Balogun, Onesimus Mahdi, Khadijat Abubakar Bobbo, Felix Olu AyegbusiJournal of Experimental and Clinical Anatomy 2018 17(1):1-7CONTEXT: Musa paradisiaca (Banana) fruit pulp has been used in folk medicine to treat various kinds of ailments, such as dysentery, diarrhea, bronchitis, ulcer, fevers, and hemorrhages...
Αλέξανδρος Γ. Σφακιανάκης
21m
19th Internarional Symposium of ISTU 5th European Symposium of EUFUS Barcelona 2019 | 13th - 15th...
19th Internarional Symposium of ISTU5th European Symposium of EUFUSBarcelona 2019 | 13th - 15th JuneABSTRACT BOOK ORGANIZING COMMITEEScientific Organizing CommitteeRobin Cleveland, Co-Chair Vera Khokhlova, Co-ChairLocal Organizing CommitteeJoan Vidal-Jové, ChairEUFUS Organizing CommitteeAndreas Melzer, Co-Chair Wladyslaw Gedroyc Alessandro Napoli Matthias Matzko Lisa Landgraf ISTUJoo Ha Hwang, President Kim Butts Pauly, Secretary General Jean-François Aubry Gail ter Haar Thursday, June 13th 2019Friday,...
Αλέξανδρος Γ. Σφακιανάκης
22m
Investigation of Complications Following Port Insertion in a Cancer Patient Population: A Retrospective...
Investigation of Complications Following Port Insertion in a Cancer Patient Population: A Retrospective AnalysisWilliam Paul Skelton, IV1, Aaron J Franke1, Samantha Welniak1, Raphael C Bosse1, Fares Ayoub1, Martina Murphy2, Jason S Starr2First Published April 24, 2019.https://doi.org/10.1177/1179554919844770AbstractHide PreviewAbstractCentral venous access devices, specifically implantable ports, play an essential role in the care of oncology patients; however, complications are prevalent. This retrospective...
Αλέξανδρος Γ. Σφακιανάκης
29m
Follicular Dendritic Cell Sarcoma or Not? A Series of 5 Diagnostically Challenging Cases Nicolas Lopez-Hisijos,...
Follicular Dendritic Cell Sarcoma or Not? A Series of 5 Diagnostically Challenging CasesNicolas Lopez-Hisijos, Reeba Omman, Stefan Pambuccian, Kamran MirzaFirst Published May 23, 2019.https://doi.org/10.1177/1179554919844531AbstractHide PreviewAbstractImperfect or unusual presentation, morphology, or immunophenotype can make the diagnosis of follicular dendritic cell sarcoma (FDCS) very challenging. To illustrate this, we present 5 unique cases from the archives of our tertiary care academic medical...
Αλέξανδρος Γ. Σφακιανάκης
29m
Improvement of Chemotherapy Solutions Production Procedure in a Hospital Central Chemotherapy Preparation...
Improvement of Chemotherapy Solutions Production Procedure in a Hospital Central Chemotherapy Preparation Unit: A Systematic Risk Assessment to Prevent Avoidable Harm in Cancer PatientsKlio Bourika1, Angelos Koutras2, Haralambos Kalofonos2, Anna Vicha3, Ekaterini Tsiata4, Evangelia Papadimitriou1, Konstantinos Avgoustakis5, Zoi Panagi4AbstractObjective:This study was designed to reevaluate and improve the quality and safety of the chemotherapy preparation in a Central Chemotherapy Preparation Unit...
Αλέξανδρος Γ. Σφακιανάκης
29m
The Nephroprotective Effect of Mannitol in Head and Neck Cancer Patients Receiving Cisplatin Therapy...
The Nephroprotective Effect of Mannitol in Head and Neck Cancer Patients Receiving Cisplatin TherapyErik Hägerström1, Lotte Lindberg2, Jens Bentzen3, Kasper Brødbæk4, Bo Zerahn2, Bent Kristensen2Introduction:Cisplatin is used as treatment for several different malignancies and a well-known complication is irreversible kidney damage. To protect the kidneys, this treatment is often combined with mannitol infusion to promote osmotic diuresis. Earlier studies investigating the nephroprotective effect...
Αλέξανδρος Γ. Σφακιανάκης
31m
Correlation Between the Sites of Onset of Basal Cell Carcinoma and the Embryonic Fusion Planes in the...
Correlation Between the Sites of Onset of Basal Cell Carcinoma and the Embryonic Fusion Planes in the AuricleGiovanni Nicoletti123, Marco Mario Tresoldi13, Alberto Malovini4, Sebastien Prigent1, Manuela Agozzino5, Angela Faga236AbstractObjectives:This study aims at the identification of the distribution of basal cell carcinomas (BCCs) in the auricle in correlation with the currently most credited sites of the embryonic fusion planes of the auricle.Methods:An overall number of 69 patients with 72...
Αλέξανδρος Γ. Σφακιανάκης
32m
A Rare Primary Tumor of the Thyroid Gland: A New Case of Leiomyoma and Literature Review, Yanling Zhang12, Heng...
A Rare Primary Tumor of the Thyroid Gland: A New Case of Leiomyoma and Literature Review,Yanling Zhang12, Heng Tang2, Huaiyuan Hu2, Xiang Yong2AbstractPrimary leiomyomas of the thyroid are very rare. We here report a case of a 53-year-old woman with a painless mass at the right thyroid, revealed by physical examination. The patient underwent a lobectomy. Frozen sections showed a spindle cell tumor of the thyroid gland. The nuclei of some of the tumor cells were obviously enlarged and deeply stained....
Αλέξανδρος Γ. Σφακιανάκης
33m
Clinical Medicine Insights: Oncology
Articles 1 – 20 of 343Original ResearchOpen AccessEpidemiological Determinants of Advanced Prostate Cancer in Elderly Men in the United StatesJinani Jayasekera1, Eberechukwu Onukwugha2, Christopher Cadham1, Sarah Tom3, Donna Harrington4, Michael Naslund5First Published June 26, 2019.https://doi.org/10.1177/1179554919855116AbstractHide PreviewAbstractIn this study, we examined the effects of individual-level and area-level characteristics on advanced prostate cancer diagnosis among Medicare eligible...
Αλέξανδρος Γ. Σφακιανάκης
33m
Pain management and prescribing practices in otolaryngology residency programs☆, Author links open overlay...
Pain management and prescribing practices in otolaryngology residency programs☆,Author links open overlay panelJaclynKlimczakArvindBadheyAnniWongPatrickColleyMaritaTengDepartment of Otolaryngology Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USAReceived 12 May 2019, Available online 18 July 2019.Show lesshttps://doi.org/10.1016/j.amjoto.2019.07.009Get rights and contentAbstractPurposeTo understand the knowledge, competency and influencing factors regarding postoperative...
Αλέξανδρος Γ. Σφακιανάκης
36m
WHAT CAN PHYSICS AND MODELLING DO FOR NEUROSURGEONS AND NEUROLOGISTS? J.-F. Aubry1 1Physics for Medicine...
WHAT CAN PHYSICS AND MODELLING DO FOR NEUROSURGEONS AND NEUROLOGISTS? J.-F. Aubry1 1Physics for Medicine Paris, Inserm, ESPCI Paris, CNRS, PSL Research University, Paris, France e-mail: jean-francois.aubry@espci.fr OBJECTIVES This talk will give an overview of the underlying physics and modelling for transcranial brain therapy. METHODS Due to the increased defocusing effect of the human skull with increasing frequency, transcranial focusing techniques divide into two groups: (i) the use of very low...
Αλέξανδρος Γ. Σφακιανάκης
39m
CONTRIBUTION TO THERAPEUTIC ULTRASOUND. BRIEF OVERVIEW L.R. Gavrilov Acoustics Institute, Moscow, Russia,...
CONTRIBUTION TO THERAPEUTIC ULTRASOUND. BRIEF OVERVIEWL.R. GavrilovAcoustics Institute, Moscow, Russia, e-mail: lrgavrilov@gmail.comBelow is a short list of contributions to therapeutic ultrasound made with my participation. 1971. Research on the use of HIFU for local ablation of deep brain structures was initiated in theSoviet Union. (Together with the Brain Institute, Academy of Medical Sciences of the USSR). 1972-1973. The possibility of ablating deep brain structures through an intact human...
Αλέξανδρος Γ. Σφακιανάκης
40m
A HEALTHY FUTURE FOR FOCAL CONFORMAL THERAPEUTIC ULTRASOUND W.A. N'Djin1 1 LabTAU, INSERM, Centre Léon...
A HEALTHY FUTURE FOR FOCAL CONFORMAL THERAPEUTIC ULTRASOUND W.A. N'Djin1 1 LabTAU, INSERM, Centre Léon Bérard, Université Lyon 1, Univ Lyon, F-69003, Lyon, France e-mail: apoutou.ndjin@inserm.fr Therapeutic ultrasound is in constant evolution. Focal/conformal strategies are now often sought after to improve the patient care, but their development remains challenging and requires bringing together new solutions. In open surgery, we proposed an unconventional toroidal focusing strategy for USgHIFU...
Αλέξανδρος Γ. Σφακιανάκης
40m
EXPLODING DROPLETS AND SINGING BUBBLES IN THERAPEUTIC ULTRASOUND K. J. Haworth1,2 1 Department of Internal...
EXPLODING DROPLETS AND SINGING BUBBLES IN THERAPEUTIC ULTRASOUND K. J. Haworth1,2 1 Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio, USA 2 Department of Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio, USA e-mail: hawortkn@ucmail.uc.edu Though widely used clinically for diagnostic imaging, microbubbles also provide a rich opportunity for inducing bioeffects, both intended and unintended. Phase-change agents that take advantage of acoustic droplet vaporization...
Αλέξανδρος Γ. Σφακιανάκης
40m
TOWARDS AN INCREASED CLINICAL IMPACT OF FOCUSED ULTRASOUND Chrit Moonen Imaging Division, University...
TOWARDS AN INCREASED CLINICAL IMPACT OF FOCUSED ULTRASOUNDChrit MoonenImaging Division, University Medical Center, The NetherlandsE-mail C.Moonen@umcutrecht.nlHIFU is a disruptive, minimally invasive, therapeutic technology in medicine, and its historyfollows the nature cycle from the inventive stage, technical developments, preclinical andclinical applications. Following early promise by the Fry brothers, the advent of imageguidance and many technical refinements, clinical applications started with...
Αλέξανδρος Γ. Σφακιανάκης
41m
MRgFUS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS: A CLINICAL UPDATE Raul Martinez Fernandez, Centro...
MRgFUS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS: A CLINICAL UPDATE Raul Martinez Fernandez, Centro Integral en Neurociencias A.C. (HM CINAC), Madrid e-mail: rmartinez.hmcinac@hmhospitales.com Since the first studies using MRgFUS for the treatment of essential tremor came out in 2013, its applications for neurological diseases have progressively increased. Today, MRgFUS thalamotomy is a FDA-approved treatment for both essential and parkinsonian tremors and some evidence suggests that it can also...
Αλέξανδρος Γ. Σφακιανάκης
41m
Prostate Cancer Salvage Surgery, Ablation Offer Similar Outcomes, Jody A. Charnow, Editor AUA 2017,...
Prostate Cancer Salvage Surgery, Ablation Offer Similar Outcomes,Jody A. Charnow, EditorAUA 2017, doctors performing surgery, prostate cancer, biopsy, prostate biopsy, prostate surgeryRadical prostatectomy and ablation for salvage treatment of radiorecurrent prostate cancer do not differ significant with regard to cancer-specific and metastasis-free survival, a study found.Salvage radical prostatectomy (SRP) and salvage ablation (SA) therapies for localized recurrence of prostate cancer following...
Αλέξανδρος Γ. Σφακιανάκης
42m
Fishy approach to treating brain tumors
Researchers say lampreys might hold the key to getting mammalian brain tissue to accept chemotherapy drugs.source-imageJun 25, 2019By Brendan Howard, Business Channel DirectorDVM360 MAGAZINERostislav/stock.adobe.comIt's a rare veterinarian who would see a lamprey in practice, but researchers at the University of Wisconsin-Madison and University of Texas at Austin are digging into some of the animal's antigen receptors to explore a new path to treating cancer in the brain.What's a lamprey again?Lampreys,...
Αλέξανδρος Γ. Σφακιανάκης
43m
Ultrasound and Microbubbles Used to Penetrate the Blood-Brain Barrier, JUNE 27TH, 2019  MEDGADGET EDITORS MATERIALS, NEUROLOGY, NEUROSURGERY, ONCOLOGY, RADIOLOGY...
Ultrasound and Microbubbles Used to Penetrate the Blood-Brain Barrier,JUNE 27TH, 2019  MEDGADGET EDITORS MATERIALS, NEUROLOGY, NEUROSURGERY, ONCOLOGY, RADIOLOGYWhile the blood-brain barrier (BBB) protects the brain from infections, it also makes it difficult to get drugs that treat neurological conditions to where they're needed. Now, researchers at Columbia University have shown that their ultrasound technique can open up the BBB and allow for the delivery of therapeutic proteins and genes into...
Αλέξανδρος Γ. Σφακιανάκης
43m
Celsion (CLSN) Granted IRB Approval to Commence Clinical Study of ThermoDox Plus High Intensity Focused...
Celsion (CLSN) Granted IRB Approval to Commence Clinical Study of ThermoDox Plus High Intensity Focused Ultrasound,Celsion Corporation (NASDAQ: CLSN), an oncology drug-development company, announces that the University Medical Center Utrecht in the Netherlands has received Institutional Review Board (IRB) approval to begin a Phase I study to determine the safety, tolerability and feasibility of ThermoDox® (lyso-thermosensitive liposomal doxorubicin) in combination with Magnetic Resonance Guided High...
Αλέξανδρος Γ. Σφακιανάκης
44m
FOCUSED ULTRASOUND FOR THE TREATMENT OF ESSENTIAL TREMOR TARGETING THE VENTRALIS INTERMEDIUS NUCLEUS AND THE ZONA INCERTA
Research Spotlight: New Targets in Treating Essential Tremor ,A team in London has developed a new method for treating essential tremor patients involving ablating two areas in the brain. READ MORE >BEYOND THE THALAMUS - UNILATERAL MR GUIDED FOCUSED ULTRASOUND FORTHE TREATMENT OF ESSENTIAL TREMOR TARGETING THE VENTRALISINTERMEDIUS NUCLEUS AND THE ZONA INCERTAA.J. Jameel1, P.G. Bain2, D Nandi1, B Jones1, O Kirmi1, W Gedroyc11Imperial College NHS Healthcare Trust, London. 2Imperial College of Science...
Αλέξανδρος Γ. Σφακιανάκης
47m
CarThera's low-intensity pulsed ultrasound device, the SonoCloud, is designed to temporarily open the blood-brain barrier (BBB), potentially improving the penetration of therapeutic agents into the brain to increase efficacy.
FDA Approves New Focused Ultrasound Trial to Treat Deadly Brain Tumors ,French manufacturer, CarThera, recently announced that the US Food & Drug Administration (FDA) has granted approval to begin a US clinical trial of their SonoCloud-9 ultrasound device in patients with recurrent glioblastoma (GBM).READ MORE >CARTHERA RECEIVES FDA APPROVAL FOR PHASE 1/2A TRIAL IN GLIOBLASTOMASonoCloud ultrasound device for glioblastoma patients will be tested for first time at US clinical sitesCategory:...
Αλέξανδρος Γ. Σφακιανάκης
50m
Critique, Tweaked,Tom Perrin Critique, Tweaked Guilty Aesthetic Pleasures , Timothy Aubry. Harvard...
Critique, Tweaked,Tom PerrinCritique, TweakedGuilty Aesthetic Pleasures , Timothy Aubry. Harvard University Press, 2018.Paraliterary: The Making of Bad Readers in Postwar America , Merve Emre. Chicago University Press, 2017.Guilty Pleasures: Popular Novels and American Audiences in the Long Nineteenth Century , Hugh McIntosh. University of Virginia Press, 2018.Elements of Surprise: Our Mental Limits and the Satisfactions of Plot , Vera Tobin. Harvard University Press, 2018.Tom PerrinAmerican Literary...
Αλέξανδρος Γ. Σφακιανάκης
50m
Projected number of people with onchocerciasis-loiasis co-infection in Africa, 1995 to 2025,  Natalie...
Projected number of people with onchocerciasis-loiasis co-infection in Africa, 1995 to 2025,  Natalie V S Vinkeles Melchers; Luc E Coffeng; Michel Boussinesq ; Belén Pedrique; Sébastien D S Pion ...
Αλέξανδρος Γ. Σφακιανάκης
52m
Trauma and Acute Care Surgery
Helmet Use is Associated with Higher Injury Severity Scores in Alpine Skiers and Snowboarders Evaluated at a Level 1 Trauma CenterBackground There is uncertainty regarding the efficacy of ski helmets in preventing traumatic injury. We investigated the relationship between helmet use, injury types and injury severity among skiers and snowboarders. Methods The trauma registry at a Northeast ACS Level 1 trauma center was queried by ICD 9/10-code for skiing and snowboarding injury between 2010 and 2018....
Αλέξανδρος Γ. Σφακιανάκης
53m

The power of mantis shrimp strikes: interdisciplinary impacts of an extreme cascade of energy release,  S...
The power of mantis shrimp strikes: interdisciplinary impacts of an extreme cascade of energy release,  S N Patek 
Αλέξανδρος Γ. Σφακιανάκης
55m
Pitfalls of a Shared Neuraxial Space: Wandering Epidural Catheter,  Rani A. Sunder, M.D.; Eric J. Monroe,...
Pitfalls of a Shared Neuraxial Space: Wandering Epidural Catheter, Rani A. Sunder, M.D.; Eric J. Monroe, M.D.; Sean H. Flack, M.B., Ch.B., F.C.A.Anesthesiology Published online July 17, 2019. doi:10.1097/ALN.0000000000002900Newly PublishedImages in Anesthesiology  |   July 2019Pitfalls of a Shared Neuraxial Space: Wandering Epidural CatheterRani A. Sunder, M.D.; Eric J. Monroe, M.D.; Sean H. Flack, M.B., Ch.B., F.C.A. Author NotesFrom the Department of Anesthesiology and Pain Medicine (R.A.S., S.H.F.),...
Αλέξανδρος Γ. Σφακιανάκης
57m
Anesthesiology
CorrespondenceCrystalloid/Colloid Renal and Disability Outcomes: CommentReuven Pizov, M.D.; Simon Gelman, M.D., Ph.D.Anesthesiology Published online July 17, 2019. doi:10.1097/ALN.0000000000002873Crystalloid/Colloid Renal and Disability Outcomes: ReplyAlexandre Joosten, M.D., Ph.D.; Joseph Rinehart, M.D.; Philippe Van der Linden, M.D., Ph.D.Anesthesiology Published online July 17, 2019. doi:10.1097/ALN.0000000000002874Images in AnesthesiologyPitfalls of a Shared Neuraxial Space: Wandering Epidural...
Αλέξανδρος Γ. Σφακιανάκης
58m
Quantitative Brain Sodium MRI Depicts Corticospinal Impairment in Amyotrophic Lateral Sclerosis Aude-Marie...
Quantitative Brain Sodium MRI Depicts Corticospinal Impairment in Amyotrophic Lateral SclerosisAude-Marie Grapperon, Ben Ridley, Annie Verschueren, Adil Maarouf, Sylviane Confort-Gouny, Etienne Fortanier, Lothar Schad, Maxime Guye, Jean-Philippe Ranjeva,  … Show all AuthorsAuthor AffiliationsFrom the Aix Marseille University, CRMBM, UMR CNRS 7339, 27 Boulevard Jean Moulin, 13005 Marseille, France (A.M.G., B.R., A.V., A.M., S.C., E.F., M.G., J.P.R., W.Z.); APHM, Hôpital de la Timone, Referral Centre...
Αλέξανδρος Γ. Σφακιανάκης
59m
Contrast-enhanced chest and abdominopelvic CT and/or whole-body fluorine 18 fluorodeoxyglucose PET/CT for initial staging, as well as for recurrence of suspected primary central nervous system lymphoma, had a low diagnostic yield.
Primary Central Nervous System Lymphoma: Diagnostic Yield of Whole-Body CT and FDG PET/CT for Initial Systemic ImagingChong Hyun Suh, Ho Sung Kim , Ji Eun Park, Seung Chai Jung, Choong Gon Choi, Sang Joon KimAuthor AffiliationsFrom the Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Olympic-ro 33, Seoul 05505, Republic of Korea.Address correspondence to H.S.K. (e-mail: radhskim@gmail.com).Published Online:Jun 25 2019https://doi.org/10.1148/radiol.2019190133See...
Αλέξανδρος Γ. Σφακιανάκης
59m
Inferior Vena Cava Thrombosis in Behçet Disease, Furkan Ufuk Author Affiliations From Pamukkale University,...
Inferior Vena Cava Thrombosis in Behçet Disease,Furkan Ufuk Author AffiliationsFrom Pamukkale University, School of Medicine, Department of Radiology, 20070, Denizli, Turkey.Address correspondence to F.U. (e-mail: furkan.ufuk@hotmail.com).Published Online:Jun 18 2019https://doi.org/10.1148/radiol.2019190351
Αλέξανδρος Γ. Σφακιανάκης
1h
Breast Imaging,          Influence of Mammography Volume on Radiologists' Performance: Results...
Breast Imaging,        Influence of Mammography Volume on Radiologists' Performance: Results from BreastScreen NorwaySolveig Roth Hoff, Tor-Åge Myklebust...Solveig HofvindEditorial: Optimizing Breast Cancer Screening Programs: Experience and StructuresRobert D. Rosenberg, David SeidenwurmMammography, US, and MRI to Assess Outcomes of Invasive Breast Cancer with Extensive Intraductal Component: A Matched Cohort StudySu Min Ha, Joo Hee Cha...Hak Hee KimEditorial: Breast Cancer: Let Imaging Be Our Guide...
Αλέξανδρος Γ. Σφακιανάκης
1h
Radiology
Review Imaging Diagnosis and Follow-up of Advanced Prostate Cancer: Clinical Perspectives and State of the Art Raquel Perez-Lopez, Nina Tunariu...Dow-Mu KohImages in Radiology Large Intussusception after Total GastrectomySo Hyun Kang, Sang-Hoon AhnInferior Vena Cava Thrombosis in Behçet Disease Furkan UfukOriginal ResearchBreast Imaging Influence of Mammography Volume on Radiologists' Performance: Results from BreastScreen NorwaySolveig Roth Hoff, Tor-Åge Myklebust...Solveig HofvindEditorial: Optimizing...
Αλέξανδρος Γ. Σφακιανάκης
1h
Imaging findings of subcutaneous human dirofilariasis, Author links open overlay panelSyed IntakhabAlamMDaPankajNepalMDbSong...
Imaging findings of subcutaneous human dirofilariasis,Author links open overlay panelSyed IntakhabAlamMDaPankajNepalMDbSong ChiLucAhmedElramadidJoshua M.SapireMDeaHamad Medical Corporation, Doha, QatarbSt. Vincent's Medical Center, Bridgeport, CT, USAcFrank H. Netter MD School of Medicine, North Haven, CT, USAdHamad Medical Corporation, Doha, QatareSt. Vincent's Medical Center, Bridgeport, CT, USAAvailable online 12 July 2019.Show lesshttps://doi.org/10.1067/j.cpradiol.2019.07.001Get rights and contentAbstractDirofilariasis...
Αλέξανδρος Γ. Σφακιανάκης
1h
Current Problems in Diagnostic Radiology
How many radiographs does it take to screen for femoral cam morphology?: A non-inferiority studyPublication date: Available online 12 July 2019Source: Current Problems in Diagnostic RadiologyAuthor(s): Tony T. Wong, Joanna K. Weeks, Firas S. Ahmed, Mark A. Francescone, Michael J. Rasiej, Michael Z. Liu, Jonathan K. KazamAbstractPurposeTo compare a 2-view radiograph series (AP of the pelvis and 45° Dunn of the hip) with a 5-view radiograph series for sensitivity in identifying femoral cam morphology.Materials...
Αλέξανδρος Γ. Σφακιανάκης
1h
"Genetic and genomic alterations differentially dictate low-grade glioma growth through cancer stem...
"Genetic and genomic alterations differentially dictate low-grade glioma growth through cancer stem cell-specific chemokine recruitment of T cells and microglia", Guo et al. 2019, Neuro-Oncology  Marlene Arzt; Michelle Monje
Αλέξανδρος Γ. Σφακιανάκης
1h
Otology & Neurotology
Speech Perception Growth Patterns in Prelingual Deaf Children With Bilateral Sequential Cochlear ImplantationObjective: To evaluate speech perception following the first (CI-1) and second (CI-2) cochlear implantation (CI) in children with sequential bilateral CI. Study Design: Retrospective. Patients: Seventy children with follow-up for 60 months post CI-1 and 36 months post CI-2. Main Outcome Measures: Word recognition score (WRS) was the main outcome. WRSs were compared by age at CI operation (group...
Αλέξανδρος Γ. Σφακιανάκης
1h
Antimicrobial resistance three ways: healthcare crisis, major concepts, and the relevance of biofilms,  Paula...
Antimicrobial resistance three ways: healthcare crisis, major concepts, and the relevance of biofilms,  Paula Jorge; Andreia Patrícia Magalhães; Tânia Grainha; Diana Alves ; Ana Margarida Sousa ...
Αλέξανδρος Γ. Σφακιανάκης
1h
Weaving Chiapas: Maya Women's Lives in a Changing World. Edited by Yolanda Castro Apreza, Charlene M....
Weaving Chiapas: Maya Women's Lives in a Changing World. Edited by Yolanda Castro Apreza, Charlene M. Woodcock, and A.C. K'inal Antsetik,  Daisy R Herrera  Nothing to Speak of: Wartime Experiences of the Danish Jews 1943-1945. By Sofie Lene Bak  Frances E Davey
Αλέξανδρος Γ. Σφακιανάκης
1h
The Resilience of Religion in American Higher Education. By John Schmalzbauer and Kathleen A. Mahoney,  Perry...
The Resilience of Religion in American Higher Education. By John Schmalzbauer and Kathleen A. Mahoney,  Perry L Glanzer  The Holy Roman Empire. A Short History. By Barbara Stollberg-Rilinger. Translated and with a Preface by Yair Mintzker  Joachim Whaley  Armenian Christians in Iran: Ethnicity, Religion and Identity in the Islamic Republic. By James Barry  Houri Berberian  Pope Eugenius III (1145-1153): The First Cistercian Pope. Edited by Iben Fonnesberg-Schmidt and Andrew Jotischky  Katharine Sykes  Dagger...
Αλέξανδρος Γ. Σφακιανάκης
1h
Guidelines for Adult Stroke Rehabilitation and Recovery,   Michelle Gittler, MD1; Andrew M. Davis,...
Guidelines for Adult Stroke Rehabilitation and Recovery, Michelle Gittler, MD1; Andrew M. Davis, MD, MPH2Author Affiliations Article Information1Schwab Rehabilitation Hospital, Chicago, Illinois2University of Chicago, Chicago, IllinoisJAMA. 2018;319(8):820-821. doi:10.1001/jama.2017.22036Guideline title Guidelines for Adult Stroke Rehabilitation and RecoveryDeveloper American Heart Association (AHA)/American Stroke Association (ASA)Release date May 4, 2016Prior version 2005Funding source AHATarget...
Αλέξανδρος Γ. Σφακιανάκης
1h
JAMA
Guidelines for Adult Stroke Rehabilitation and RecoveryVIEWPOINTElectronic Fetal Monitoring to Prevent Fetal Brain Injury: A Ubiquitous Yet Flawed ToolEmmet Hirsch, MDJAMA CLINICAL GUIDELINES SYNOPSISManagement of Patients With Acute Ischemic StrokeJames R. Brorson, MD; Adam S. Cifu, MDTRENDING NOW ON JAMA NETWORK OPENAssociation of Preterm Birth With Social Relationships in AdulthoodAndrogen Deprivation Therapy and Dementia Diagnosis in Men With Prostate CancerAssociation of Cardiorespiratory Fitness...
Αλέξανδρος Γ. Σφακιανάκης
1h
Adding voxel-based color maps of initial and final 90-second time-signal intensity areas under the curve from dynamic contrast-enhanced MR imaging to conventional MR imaging increases the diagnostic accuracy to detect local recurrence in head and neck squamous cell carcinoma by improving the specificity without sacrificing the sensitivity.
Detection of Local Recurrence in Patients with Head and Neck Squamous Cell Carcinoma Using Voxel-Based Color Maps of Initial and Final Area under the Curve Values Derived from DCE-MRIJ.Y. Lee, K.L. Cheng, J.H. Lee, Y.J. Choi, H.W. Kim, Y.S. Sung, S.R. Chung, K.H. Ryu, M.S. Chung, S.Y. Kim, S.-W. Lee and J.H. BaekAmerican Journal of Neuroradiology July 2019, DOI: https://doi.org/10.3174/ajnr.A6130ArticleFigures & DataSupplementalInfo & MetricsReferences PDFThis article requires a subscription...
Αλέξανδρος Γ. Σφακιανάκης
1h
Distal Balloon Angioplasty of Cerebral Vasospasm Decreases the Risk of Delayed Cerebral Infarction M.-A....
Distal Balloon Angioplasty of Cerebral Vasospasm Decreases the Risk of Delayed Cerebral InfarctionM.-A. Labeyrie, S. Gaugain, G. Boulouis, A. Zetchi, J. Brami, J.-P. Saint-Maurice, V. Civelli, S. Froelich and E. HoudartAmerican Journal of Neuroradiology July 2019, DOI: https://doi.org/10.3174/ajnr.A6124ArticleFigures & DataSupplementalInfo & MetricsReferences PDFThis article requires a subscription to view the full text. If you have a subscription you may use the login form below to view...
Αλέξανδρος Γ. Σφακιανάκης
1h
Comparison of CSF and MRI Findings among Neonates and Infants with E coli or Group B Streptococcal Meningitis...
Comparison of CSF and MRI Findings among Neonates and Infants with E coli or Group B Streptococcal MeningitisS.F. Kralik, M.K. Kukreja, M.J. Paldino, N.K. Desai and J.G. VallejoAmerican Journal of Neuroradiology July 2019, DOI: https://doi.org/10.3174/ajnr.A6134ArticleFigures & DataInfo & MetricsReferences PDFThis article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.AbstractBACKGROUND...
Αλέξανδρος Γ. Σφακιανάκης
1h

Pediatrics Online eFirst Pages, (for the period 17 Jul 2019 to 18 July 2019) Article Neighborhood...
Pediatrics Online eFirst Pages,(for the period 17 Jul 2019 to 18 July 2019)ArticleNeighborhood Social Conditions, Family Relationships, and Childhood AsthmaEdith Chen, Robin Hayen, Van Le, Makeda K. Austin, Madeleine U. Shalowitz, Rachel E. Story and Gregory E. MillerCase ReportThe Challenge of Treating Pulmonary Vasculitis in Behçet Disease: Two Pediatric CasesSelcan Demir, Erdal Sag, Ummusen Kaya Akca, Tuncay Hazirolan, Yelda Bilginer and Seza OzenSpecial ArticleCognitive and Behavioral Impact...
Αλέξανδρος Γ. Σφακιανάκης
1h
Molecular and Cellular Endocrinology
Acetylation modulates thyroid hormone receptor intracellular localization and intranuclear mobilityPublication date: 15 September 2019Source: Molecular and Cellular Endocrinology, Volume 495Author(s): Cyril S. Anyetei-Anum, Rochelle M. Evans, Amanda M. Back, Vincent R. Roggero, Lizabeth A. AllisonAbstractThe thyroid hormone receptor (TR) undergoes nucleocytoplasmic shuttling, but is primarily nuclear-localized and mediates expression of genes involved in development and homeostasis. Given the proximity...
Αλέξανδρος Γ. Σφακιανάκης
1h
Uterus globulin associated protein 1 (UGRP1) is a potential marker of progression of Graves' disease...
Uterus globulin associated protein 1 (UGRP1) is a potential marker of progression of Graves' disease into hypothyroidism,Publication date: 20 August 2019Source: Molecular and Cellular Endocrinology, Volume 494Author(s): Zheng Zhou, Chun-Lin Zuo, Xue-Song Li, Xiao-Ping Ye, Qian-Yue Zhang, Ping Wang, Rong-Xin Zhang, Gang Chen, Jia-Lin Yang, Yue Chen, Qin-Yun Ma, Huai-Dong SongAbstractApproximately 20% of Graves' disease (GD) patients may result eventually in hypothyroidism in their natural course....
Αλέξανδρος Γ. Σφακιανάκης
1h
Clinical Immunology
The protective effect of interfering TLR9-IRF5 signaling pathway on the development of CVB3-induced myocarditisPublication date: October 2019Source: Clinical Immunology, Volume 207Author(s): Shu Nie, Boqi Dong, Shuang Gao, Yan Zhou, Wenting Lu, Mingli Fang, Shucheng Hua, Yongli Yu, Liying WangAbstractSince toll-like receptor 9 (TLR9) or interferon regulatory factor 5 (IRF5) was reported to be associated with the development of myocarditis, we wondered if the TLR9-IRF5 pathway could contribute to...
Αλέξανδρος Γ. Σφακιανάκης
1h
Evaluation of the frequency of invariant natural killer T (iNKT) cells in nasal polyps, Publication...
Evaluation of the frequency of invariant natural killer T (iNKT) cells in nasal polyps,Publication date: August 2019Source: Clinical Immunology, Volume 205Author(s): Mohammad Fereidouni, Afshin Derakhshani, Simon Yue, Saeed Nasseri, Reza Farid Hosseini, Mehdi Bakhshaee, Fatemeh Vahidian, Mark A. ExleyAbstractNasal polyps (NP) are associated with inflamed mucosa of unknown etiology. The role of T cells in nasal polyposis is unclear. Invariant natural killer T cells (iNKT) can promote Th2 responses...
Αλέξανδρος Γ. Σφακιανάκης
1h
Molecular Testing for Indeterminate Thyroid Nodules—When the Rubber Meets the Road Jennifer L. Marti, MD1; Ashok...
Molecular Testing for Indeterminate Thyroid Nodules—When the Rubber Meets the RoadJennifer L. Marti, MD1; Ashok R. Shaha, MD2Author Affiliations Article Information1Department of Surgery, Endocrine & Breast Surgery, Weill Cornell Medical Center, New York, New York2Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New YorkJAMA Otolaryngol Head Neck Surg. Published online July 18, 2019. doi:10.1001/jamaoto.2019.1465related articles icon RelatedArticlesIn...
Αλέξανδρος Γ. Σφακιανάκης
1h
Saline Irrigation and Topical Nasal Steroids Janalee K. Stokken, MD Article Information JAMA Otolaryngol...
Saline Irrigation and Topical Nasal SteroidsJanalee K. Stokken, MDArticle InformationJAMA Otolaryngol Head Neck Surg. Published online July 18, 2019. doi:10.1001/jamaoto.2019.1713View LargeDownloadWhy Your Physician Recommends Nasal IrrigationNasal irrigation with salt water (saline) is also called nasal wash, rinse, douche, or lavage. This is often recommended by physicians to reduce the frequency and severity of the symptoms associated with inflammation of the nose owing to allergies or other causes....
Αλέξανδρος Γ. Σφακιανάκης
1h
Plasmablastic Lymphoma of the Nasal Septum Jonathan N. Perkins, DO1,2; Anthony W. Chi, MD3; Nitinkumar...
Plasmablastic Lymphoma of the Nasal SeptumJonathan N. Perkins, DO1,2; Anthony W. Chi, MD3; Nitinkumar J. Patel, MD2Author Affiliations Article Information1Department of Otolaryngology–Head & Neck Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland2Department of Otolaryngology–Head & Neck Surgery, Kaiser Permanente–Mid Atlantic Permanente Group, Falls Church, Virginia3Department of Pathology, Kaiser Permanente Mid Atlantic, Regional Laboratory, Rockville, MarylandJAMA...
Αλέξανδρος Γ. Σφακιανάκης
1h
A Case of Childhood Hearing Loss, Lauren Buck, MD1; Kandice C. Bailey1; Jeffery D. Carron, MD1 Author...
A Case of Childhood Hearing Loss,Lauren Buck, MD1; Kandice C. Bailey1; Jeffery D. Carron, MD1Author Affiliations Article Information1Department of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, JacksonJAMA Otolaryngol Head Neck Surg. Published online July 18, 2019. doi:10.1001/jamaoto.2019.1701CaseAn 8-year-old boy accompanied by his mother presented with hearing loss. The patient failed a school-administered hearing screening as well as a subsequent hearing...
Αλέξανδρος Γ. Σφακιανάκης
1h
American Journal of Neuroradiology, Publication Preview articles for 18 July 2019 HEAD & NECK...
American Journal of Neuroradiology,Publication Preview articles for 18 July 2019HEAD & NECKDetection of Local Recurrence in Patients with Head and Neck Squamous Cell Carcinoma Using Voxel-Based Color Maps of Initial and Final Area under the Curve Values Derived from DCE-MRIJ.Y. Lee, K.L. Cheng, J.H. Lee, Y.J. Choi, H.W. Kim, Y.S. Sung, S.R. Chung, K.H. Ryu, M.S. Chung, S.Y. Kim, S.-W. Lee and J.H. BaekAJNR Am J Neuroradiol first published on 18 July 2019 doi:10.3174/ajnr.A6130http://www.ajnr.org/content/early/2019/07/18/ajnr.A6130.abstractINTERVENTIONALA...
Αλέξανδρος Γ. Σφακιανάκης
1h
The Need for Routine Assessment of Masseter Function After Masseteric Nerve Harvest With the Borschel...
The Need for Routine Assessment of Masseter Function After Masseteric Nerve Harvest With the Borschel Method,Elena Pescarini, MD1,2; Catriona Neville, BSc1; Tamsin Gwynn, BSc1; et al Karen Young, BSc1; Lekha Chandrasekharan, FRCR, DNB(Radiodiagnosis)3; Charles Nduka, MA(Oxon), MD, FRCSEng, FRCS(Plast)1; Ruben Yap Kannan, MB, MRCSEd, PhD, FRCS(Plast), Dip(Otol)HNS1Author Affiliations Article Information1Facial Palsy Unit, Queen Victoria Hospital, East Grinstead, United Kingdom2Department of Plastic...
Αλέξανδρος Γ. Σφακιανάκης
1h
JAMA Otolaryngology–Head & Neck Surgery
ORIGINAL INVESTIGATIONComparison of Postmarketing Findings vs the Initial Clinical Validation Findings of a Thyroid Nodule Gene Expression Classifier: A Systematic Review and Meta-analysisPablo Valderrabano, MD, PhD; Julie E. Hallanger-Johnson, MD; Ram Thapa, PhD; et al.Invited Commentary: Molecular Testing for Indeterminate Thyroid Nodules—When the Rubber Meets the Road ; Jennifer L. Marti, MD; Ashok R. Shaha, MDAssessment of Voice Outcomes Following Surgery for Thyroid CancerKevin J. Kovatch, MD;...
Αλέξανδρος Γ. Σφακιανάκης
1h
Geopolitics Turned Inwards: The Princeton Military Studies Group and the National Security Imagination,  Dexter...
Geopolitics Turned Inwards: The Princeton Military Studies Group and the National Security Imagination,  Dexter Fergie
Αλέξανδρος Γ. Σφακιανάκης
1h
3D Research
A Multi-sprite Based Anaglyph 3D Video Watermarking Approach Robust Against CollusionAbstract3D video watermarking is far from the maturity of watermarking algorithms dedicated to audio, image or 2D video. In fact, little work has been proposed for anaglyph 3D videos. Such methods have not been robust against malicious attacks such as compression and collusion. The latter one is a very dangerous attack that can be applied on video content and can easily remove an embedded signature to obtain original...
Αλέξανδρος Γ. Σφακιανάκης
1h
Threats Underestimated in Freshwater Plastic Pollution: Mini-Review Abstract Plastic pollution is one...
Threats Underestimated in Freshwater Plastic Pollution: Mini-ReviewAbstractPlastic pollution is one of the most acute environmental topics of our time. While there is a great scientific effort to tackle this problem, it has not always been well-coordinated or properly targeted. In this short review, we call for scientists to get involved in three crucial topics (threats) underestimated—or ignored—in freshwater systems: (i) plastic-species entanglement, (ii) plastic as nesting material, and (iii)...
Αλέξανδρος Γ. Σφακιανάκης
1h
Water, Air, & Soil Pollution
Incorporation of Electrochemically Exfoliated Graphene Oxide and TiO 2 into Polyvinylidene Fluoride-Based Nanofiltration Membrane for Dye RejectionAbstractIn this work, the novel direct synthesis method of dimethylacetamide-based graphene oxide (GO) was performed through electrochemical exfoliation assisted by commercially available single-tail sodium dodecyl sulphate (SDS) surfactant. Then, the synthesised GO (SDS–GO) was incorporated into polyvinylidene fluoride (PVDF) solution to produce a nanofiltration...
Αλέξανδρος Γ. Σφακιανάκης
1h
Adolescent stress increases depression-like behaviors and alters the excitatory-inhibitory balance
 in aged miceBackground: Depression affects approximately 5% of elderly people and its etiology might be related to chronic stress exposure during neurodevelopmental periods. In this study, we examined the effects of adolescent chronic social stress in aged mice on depressive behaviors and the excitatory-inhibitory (E/I) balance in stress-sensitive regions of the brain. Methods: Sixty-four adolescent, male C57BL/6 mice were randomly assigned to either the 7-week (from post-natal days 29 to 77) social...
Αλέξανδρος Γ. Σφακιανάκης
1h
Ectodermal dysplasia
Anhidrotic X-Linked Ectodermal DysplasiasAnodontiaBook SyndromeChaund's Ectodermal DysplasiasChondroectodermal DysplasiasChrist-Siemans-Touraine SyndromeCloustons SyndromeCurly Hair-Ankyloblephanon-Nail DysplasiaDentooculocutaneous SyndromeEctrodactyly Ectodermal Dysplasias Clefting SyndromeEllis-van Creveld SyndromeFacial Ectodermal DysplasiasFreire-Maia SyndromeGorlin's SyndromeHidrotic Ectodermal DysplasiasHypohidrotic Ectodermal Dysplasias, AutorecessiveHypoplastic Enamel-Onycholysis-HypohidrosisIncontinentia...
Αλέξανδρος Γ. Σφακιανάκης
1h
Deafness oligodontia syndrome | Genetic and Rare Diseases ..., https://rarediseases.info.nih.gov/diseases/1698/deafness-oligodontia-syndrome...
Deafness oligodontia syndrome | Genetic and Rare Diseases ...,https://rarediseases.info.nih.gov/diseases/1698/deafness-oligodontia-syndromeA collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Deafness oligodontia ...Deafness oligodontia syndromeOther Names: Congenital profound sensorineural deafness and oligodontia; Autosomal recessive sensorineural hearing impairment, dizziness, and hypodontiaCategories: Congenital and...
Αλέξανδρος Γ. Σφακιανάκης
1h
Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome
Clinical and electrophysiological profiles in early recognition of polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndromeBackground: The detection of polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome at early stage is challenging for neurologists. Since polyneuropathy could be the first manifestation, it could be misdiagnosed as chronic inflammatory demyelinating polyneuropathy (CIDP). The present study aimed to determine the clinical...
Αλέξανδρος Γ. Σφακιανάκης
1h
Risk factors for acute kidney injury in patients with acute myocardial infarction, Background: Acute...
Risk factors for acute kidney injury in patients with acute myocardial infarction,Background: Acute kidney injury (AKI) is a serious and fatal complication of acute myocardial infarction (AMI). It has high short- and long-term mortality rates and a poor prognosis but is potentially preventable. However, the current incidence, risk factors, and outcomes of AKI in the Chinese population are not well understood and would serve the first step to identify high-risk patients who could receive preventative...
Αλέξανδρος Γ. Σφακιανάκης
1h
Endothelial function and T-lymphocyte subsets in patients with overlap syndrome of chronic obstructive...
Endothelial function and T-lymphocyte subsets in patients with overlap syndrome of chronic obstructive pulmonary disease and obstructive sleep apneaBackground: The coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is termed overlap syndrome (OS). COPD and OSA both have increased risks of developing cardiovascular diseases. This study aimed to explore if patients with OS exhibited a higher prevalence of cardiovascular complications, and if patients with...
Αλέξανδρος Γ. Σφακιανάκης
1h
Chinese Medical Journal
Factors associated with unprotected anal intercourse among male students who have sex with men in three Northern regions of ChinaBackground: Unprotected anal intercourse (UAI) has previously been associated with human immunodeficiency virus (HIV) infection. Male students who have sex with men (SMSM) are at increased exposure to experience UAI. The aim of this study was to investigate the status of UAI and related factors among SMSM in three northern regions of China. Methods: From November 2018 to...
Αλέξανδρος Γ. Σφακιανάκης
1h
Anti-Cancer Drugs
Melanoma: the new perspectives from clinical and translational researchThe prognosis of metastatic melanoma has not changed throughout the 20th century. However, in the last decade, we have witnessed a continuous improvement in survival, with many long-term survivors. These results are largely because of the simultaneous development of the knowledge in the biology of metastatic malignant melanoma and of the relationship between the disease and the host's immune system that allowed the development...
Αλέξανδρος Γ. Σφακιανάκης
1h
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Solid Pseudopapillary Neoplasms of the Pancreas: Clinicopathologic and Radiologic Features According...Solid Pseudopapillary Neoplasms of the Pancreas: Clinicopathologic and Radiologic Features According to SizeRiccardo De Robertis1, Giovanni Marchegiani2, Matteo Catania3, Maria Chiara Ambrosetti3, Paola Capelli4, Roberto Salvia2 and Mirko D'Onofrio3 Show lessShare Share+ Affiliations:Citation: American Journal of Roentgenology: 1-8. 10.2214/AJR.18.20715AbstractFull TextReferencesPDFPDF PlusAdd to...
Αλέξανδρος Γ. Σφακιανάκης
23h
Auris Nasus Larynx
Endoscopic sinus surgery with and without computer assisted navigation: A retrospective studyPublication date: August 2019Source: Auris Nasus Larynx, Volume 46, Issue 4Author(s): Bruno Galletti, Francesco Gazia, Francesco Freni, Federico Sireci, Francesco GallettiAbstractObjectiveIn the last years endoscopic sinus surgery (ESS) is improved with the introduction of computer assisted navigation (CAN). In this retrospective study we evaluated the usefulness of CAN in endoscopic sinus surgery and studied...
Αλέξανδρος Γ. Σφακιανάκης
1d
Dermatologic Surgery
Aesthetic Outcomes of Nasal Burow's Grafts With Interdomal Sutures After Mohs Micrographic SurgeryBACKGROUND Post-Mohs reconstruction of distal nasal defects is challenging. Many repair options exist, each with advantages and disadvantages. Utilization of a Burow's graft in combination with manipulation of the underlying nasal cartilages with interdomal sutures is an underreported yet effective repair option. OBJECTIVE To present the authors' experience with Burow's grafts facilitated by interdomal...
Αλέξανδρος Γ. Σφακιανάκης
1d
The contribution by MRI and CT in the clinical staging of early glottic cancer (T1-T2) for the evaluation of submucosal areas that can change the stage of the disease and reassess the therapeutic approach. In particular, MRI shows a sensitivity of 100% and a specificity of 97% in assessing areas such as paraglottic space, anterior commissure, thyroid, and arytenoid cartilages, with various indications for conservative surgery. Instead, the sensitivity of CT reaches lower values, 40%, but it has high specificity (100%). In our series, CT staging was accurate in 70% of cases, while the MRI was accurate in 80% of cases.
Early Glottic Cancer: Role of MRI in the Preoperative Staginghttps://www.hindawi.com/journals/bmri/2014/890385/  Eugenia Allegra,1 Pierpaolo Ferrise,1 Serena Trapasso,1 Orazio Trapuzzano,2 Antonio Barca,2 Stefania Tamburrini,3 and Aldo Garozzo11Department of Experimental and Clinical Medicine-Otolaryngology Head and Neck Surgery, University of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy2Department of Experimental and Clinical Medicine-Radiology, University of Catanzaro, Viale...
Αλέξανδρος Γ. Σφακιανάκης
1d
Computer Assisted Tomography
Imaging of Usual and Unusual Complication of Rotator Cuff RepairSeveral complications may be encountered after rotator cuff (RC) repair. A thorough knowledge of surgical interventions, normal postoperative findings, and postoperative complications is crucial to provide a timely diagnosis, improving the clinical outcome of patients. Postoperative complications may involve RC, implanted device, osteochondral tissue, surgical-site infection, peripheral nerves, soft tissues, and vascular structures....
Αλέξανδρος Γ. Σφακιανάκης
1d
Bone & Joint Surgery
Publons: The Next Step in Reviewer RecognitionNo abstract availableWhat's New in Orthopaedic TraumaNo abstract availableUse of Povidone-Iodine Irrigation Prior to Wound Closure in Primary Total Hip and Knee Arthroplasty: An Analysis of 11,738 CasesBackground: Povidone-iodine (PI) irrigation is often used prior to wound closure in total joint arthroplasty, but there are limited reports evaluating its efficacy in decreasing joint infections. The goal of this study was to compare the rate of any reoperation...
Αλέξανδρος Γ. Σφακιανάκης
1d
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Ear, Nose & Throat Journal- Volume: 98, Number: 6 (July 2019) EditorialAccess to Quaternary Care:...Ear, Nose & Throat Journal- Volume: 98, Number: 6 (July 2019)EditorialAccess to Quaternary Care: Studies Needed in OtolaryngologyRobert T. SataloffOtoscopic ClinicExophytic CholesteatomaMarcus L. Elias and Robert W. JyungRhinoscopic ClinicEndoscopic View of Fungus Ball in the Most Posterior Ethmoid Cell via the Supreme MeatusJae Hoon LeeLaryngoscopic ClinicsAn Unusual Hypopharyngeal Foreign...
Αλέξανδρος Γ. Σφακιανάκης
2d





Otology & Neurotology
Speech Perception Growth Patterns in Prelingual Deaf Children With Bilateral Sequential Cochlear ImplantationObjective: To evaluate speech perception following the first (CI-1) and second (CI-2) cochlear implantation (CI) in children with sequential bilateral CI. Study Design: Retrospective. Patients: Seventy children with follow-up for 60 months post CI-1 and 36 months post CI-2. Main Outcome Measures: Word recognition score (WRS) was the main outcome. WRSs were compared by age at CI operation (group...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
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Anti-Cancer Drugs
Melanoma: the new perspectives from clinical and translational researchThe prognosis of metastatic melanoma has not changed throughout the 20th century. However, in the last decade, we have witnessed a continuous improvement in survival, with many long-term survivors. These results are largely because of the simultaneous development of the knowledge in the biology of metastatic malignant melanoma and of the relationship between the disease and the host's immune system that allowed the development...
Medicine by Alexandros G. Sfakianakis
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