Στην βιολογία, το περιβάλλον μπορεί να καθοριστεί σαν ενα σύνολο κλιματικών, βιοτικών, κοινωνικών και εδαφικών παραγόντων που δρουν σε έναν οργανισμό και καθορίζουν την ανάπτυξη και την επιβίωση του. Έτσι, περιλαμβάνει οτιδήποτε μπορεί να επηρεάσει άμεσα τον μεταβολισμό ή τη συμπεριφορά των ζωντανών οργανισμών ή ειδών, όπως το φως, ο αέρας, το νερό, το έδαφος και άλλοι παράγοντες. Δείτε επίσης το άρθρο για το φυσικό περιβάλλον και τη φυσική επιλογή.
Στην αρχιτεκτονική, την εργονομία και την ασφάλεια στην εργασία, περιβάλλον είναι το σύνολο των χαρακτηριστικών ενός δωματίου ή κτιρίου που επηρεάζουν την ποιότητα ζωής και την αποδοτικότητα, περιλαμβανομένων των διαστάσεων και της διαρρύθμισης των χώρων διαβίωσης και της επίπλωσης, του φωτισμού, του αερισμού, της θερμοκρασίας, του θορύβου κλπ. Επίσης μπορεί να αναφέρεται στο σύνολο των δομικών κατασκευών. Δείτε επίσης το άρθρο για το δομημένο περιβάλλον.
Στην ψυχολογία, περιβαλλοντισμός είναι η θεωρία ότι το περιβάλλον (με τη γενική και κοινωνική έννοια) παίζει μεγαλύτερο ρόλο από την κληρονομικότητα καθορίζοντας την ανάπτυξη ενός ατόμου. Συγκεκριμένα, το περιβάλλον είναι ένας σημαντικός παράγοντας πολλών ψυχολογικών θεωριών.
Στην τέχνη, το περιβάλλον αποτελεί κινητήριο μοχλό και μούσα εμπνέοντας τους ζωγράφους ή τους ποιητές. Σε όλες τις μορφές της Τέχνης αποτελεί έμπνευση και οι Καλές Τέχνες φανερώνουν την επιρροή οπού άσκησε σε όλους τους καλλιτέχνες με όποιο είδος Τέχνης κι αν ασχολούνται. Ο άνθρωπος μέσα στο περιβάλλον δημιουργεί Μουσική, Ζωγραφική, Ποίηση, Γλυπτική, χορό, τραγούδι, θέατρο, αλλά και όλες οι μορφές τέχνης έχουν άμεση έμπνευση από το περιβάλλον.

Τετάρτη 26 Ιουνίου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


Atmospheric Environment, Investigating fine particulate matter sources in Salt Lake City during...
Atmospheric Environment,Investigating fine particulate matter sources in Salt Lake City during persistent cold air pool eventsPublication date: Available online 24 June 2019Source: Atmospheric EnvironmentAuthor(s): Cesunica E. Ivey, Sivaraman Balachandran, Sean Colgan, Yongtao Hu, Heather A. HolmesAbstractDuring wintertime, Salt Lake City experiences periods of high-pressure atmospheric stagnation that leads to prolonged periods with stable atmospheric boundary layers (ABL) due to the unique orography...
Αλέξανδρος Γ. Σφακιανάκης
6m
BiLex: A computational approach to the effects of age of acquisition and language exposure on bilingual...
BiLex: A computational approach to the effects of age of acquisition and language exposure on bilingual lexical access17hvia Brain and LanguagePublication date: August 2019Source: Brain and Language, Volume 195Author(s): Claudia Peñaloza, Uli Grasemann, Maria Dekhtyar, Risto Miikkulainen, Swathi KiranAbstractLexical access in bilinguals can be modulated by multiple factors in their individual language learning history. We developed the BiLex computational model to examine the effects of L2 age of...
Αλέξανδρος Γ. Σφακιανάκης
9m
 Magnetic Resonance Imaging, Significant correlations between human cortical bone mineral density...
 Magnetic Resonance Imaging,Significant correlations between human cortical bone mineral density and quantitative susceptibility mapping (QSM) obtained with 3D Cones ultrashort echo time magnetic resonance imaging (UTE-MRI)Publication date: Available online 25 June 2019Source: Magnetic Resonance ImagingAuthor(s): Saeed Jerban, Xing Lu, Hyungseok Jang, Yajun Ma, Behnam Namiranian, Nicole Le, Ying Li, Eric Y. Chang, Jiang DuAbstractPurposeQuantitative susceptibility mapping (QSM) MRI is a tool that...
Αλέξανδρος Γ. Σφακιανάκης
9m
O.R.L. Journal for oto-rhino-laryngology and its borderlands, Predictive Significance of Radiographic...
O.R.L. Journal for oto-rhino-laryngology and its borderlands,Predictive Significance of Radiographic Density of Sinus Opacity and Bone Thickness in Unilateral Maxillary Sinus MycetomaObjectives: To identify the optimal cutoff value in Hounsfield units (HU) of maxillary sinus (MS) opacity and bone thickness (neo-osteogenesis) of MS as radiological predictors for mycetoma. Methods: One hundred and sixty-four patients, including 59 patients with unilateral MS mycetoma, 31 with unilateral odontogenic...
Αλέξανδρος Γ. Σφακιανάκης
10m
Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation...
Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses17hvia ScienceDirect Publication: ImmunityPublication date: Available online 24 June 2019Source: ImmunityAuthor(s): Danielle A. Chisolm, Wayne Cheng, Shelby A. Colburn, Aaron Silva-Sanchez, Selene Meza-Perez, Troy D. Randall, Amy S. WeinmannSummaryGenetic variation influences how the genome is interpreted in individuals and in mouse strains used to model...
Αλέξανδρος Γ. Σφακιανάκης
11m
Journal of Genetics and Genomics, OsGCD1, a novel player in rice intine construction Publication...
Journal of Genetics and Genomics,OsGCD1, a novel player in rice intine constructionPublication date: Available online 25 June 2019Source: Journal of Genetics and GenomicsAuthor(s): Xiaorong Huang, Mengmeng Run, Meng-Xiang SunScienceDirect Publication: Journal of Genetics and Genomics17hDissecting PCNA function with a systematically designed mutant library in yeastPublication date: Available online 24 June 2019Source: Journal of Genetics and GenomicsAuthor(s): Qingwen Jiang, Weimin Zhang, Chenghao...
Αλέξανδρος Γ. Σφακιανάκης
11m
Estrogen and estrogen receptor signaling promotes allergic immune responses: Effects on immune cells,...
Estrogen and estrogen receptor signaling promotes allergic immune responses: Effects on immune cells, cytokines, and inflammatory factors involved in allergy16hvia Allergologia et ImmunopathologiaPublication date: Available online 24 June 2019Source: Allergologia et ImmunopathologiaAuthor(s): Z. Fan, H. Che, S. Yang, C. ChenAbstractHypersensitivity occurs when the body is stimulated by an antigen, resulting in an immune response, and leads to a physiological disorder or abnormal tissue trauma. Various...
Αλέξανδρος Γ. Σφακιανάκης
11m
Oral and Maxillofacial Surgery, Knowledge, awareness, and perception of oral and maxillofacial...
Oral and Maxillofacial Surgery,Knowledge, awareness, and perception of oral and maxillofacial surgery among the public and professionals in Saudi Arabia: a cross-sectional studyPublication date: Available online 25 June 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): H. Alnofaie, B. Alchawaf, M. AlKindiAbstractAlthough oral and maxillofacial surgery (OMS) is expanding rapidly in Saudi Arabia, accurate knowledge of the specialty appears to be lacking. The aim of this...
Αλέξανδρος Γ. Σφακιανάκης
12m
 Behavioural Brain Research, Oral Ketamine Alleviates Behavioral Despair without Cognitive...
 Behavioural Brain Research,Oral Ketamine Alleviates Behavioral Despair without Cognitive Impairment in Wistar RatsPublication date: Available online 24 June 2019Source: Behavioural Brain ResearchAuthor(s): Alev Ecevitoglu, Resit Canbeyli, Gunes UnalAbstractKetamine is a non-competitive NMDA receptor antagonist used as a major anesthetic agent, especially in children. It has also been shown that at sub-anesthetic concentrations, ketamine has acute antidepressant properties. The rapid-onset nature...
Αλέξανδρος Γ. Σφακιανάκης
12m
 Macromolecular Rapid Communications, Transformation of Thioester‐Initiated Star Polymers...
 Macromolecular Rapid Communications,Transformation of Thioester‐Initiated Star Polymers into Linear Arms via Native Chemical LigationComparing different initiator types for Cu‐mediated polymerization has shown that thioester‐based initiators can be an excellent alternative that allow further conjugation via native chemical ligation, as exemplified on a star polymer using l‐cysteine methyl ester hydrochloride. Abstract The synthesis of a new class of Cu‐mediated polymerization initiators with thioester...
Αλέξανδρος Γ. Σφακιανάκης
13m
Views of professionals about the educational needs of children with neurodevelopmental disorders 16h...
Views of professionals about the educational needs of children with neurodevelopmental disorders16hvia ScienceDirect Publication: Research in Developmental DisabilitiesPublication date: August 2019Source: Research in Developmental Disabilities, Volume 91Author(s): Jo Van Herwegen, Maria Ashworth, Olympia PalikaraAbstractBackgroundProfessionals play a key role in supporting children with special educational needs in schools. However, the views of those working with neurodevelopmental disorders are...
Αλέξανδρος Γ. Σφακιανάκης
13m
Journal of Ethnopharmacology, Antioxidant, anti-inflammatory and hypoglycemic effects of <em>Fagonia...
Journal of Ethnopharmacology,Antioxidant, anti-inflammatory and hypoglycemic effects of <em>Fagonia olivieri</em> DC on STZ-nicotinamide induced diabetic rats - <em>In vivo</em> and <em>in vitro</em> studyPublication date: Available online 25 June 2019Source: Journal of EthnopharmacologyAuthor(s): Umbreen Rashid, Muhammad Rashid Khan, Moniba SajidAbstractEthnopharmacological relevanceFagonia olivieri (Zygophyllaceae) is used in Pakistan for management of diabetes...
Αλέξανδρος Γ. Σφακιανάκης
14m
Later but not early stages of familiar face recognition depend strongly on attentional resources: Evidence...
Later but not early stages of familiar face recognition depend strongly on attentional resources: Evidence from event-related brain potentials16hvia CortexPublication date: Available online 24 June 2019Source: CortexAuthor(s): Holger Wiese, Brandon T. Ingram, Megan L. Elley, Simone C. Tüttenberg, A. Mike Burton, Andrew W. YoungAbstractIn everyday life we usually recognise personally familiar faces efficiently and without apparent effort. This study examined to which extent the neural processes involved...
Αλέξανδρος Γ. Σφακιανάκης
14m
Metformin-Associated Lactic Acidosis Presenting Like Acute Mesenteric Ischemia 16h via ScienceDirect...
Metformin-Associated Lactic Acidosis Presenting Like Acute Mesenteric Ischemia16hvia ScienceDirect Publication: The Journal of Emergency MedicinePublication date: Available online 24 June 2019Source: The Journal of Emergency MedicineAuthor(s): Qi Charles Zhang, Casey Hastings, Kelly Johnson, Ellen SlavenAbstractBackgroundMetformin-associated lactic acidosis is a rare but serious complication of taking metformin. Making the diagnosis in the emergency department requires vigilance because the presentation...
Αλέξανδρος Γ. Σφακιανάκης
14m
Diagnostik und Management von Gefäßmalformationen 17m via Der Pathologe Translate article ...
Diagnostik und Management von Gefäßmalformationen17mvia Der PathologeTranslate articleZusammenfassungGefäßanomalien sind insgesamt sehr selten, können aber sowohl bei Kindern als auch bei Erwachsenen in fast jeder Körperregion auftreten. Aufgrund der Komplexität dieser vielgestaltigen Erkrankungen ist der Weg zur Diagnosestellung oft sehr schwierig und Bedarf häufig eines interdisziplinären Teamworks mit engen Absprachen zwischen den einzelnen Behandlungspartnern. Ebenso empfiehlt sich auch für die...
Αλέξανδρος Γ. Σφακιανάκης
15m
Designing Poly-agonists for Treatment of Metabolic Diseases: Challenges and Opportunities 15m ...
Designing Poly-agonists for Treatment of Metabolic Diseases: Challenges and Opportunities15mvia Latest Results for DrugsAbstractObesity, type 2 diabetes, and the numerous associated metabolic co-morbidities are growing global threats to public health. Despite recent progress in pharmacotherapies for metabolic diseases, the current treatment options have limited efficacy and provide mostly symptomatic relief with little or no impact on disease reversal. Thus, improved therapies are urgently needed....
Αλέξανδρος Γ. Σφακιανάκης
15m
Molecular Inverse Comorbidity between Alzheimer's Disease and Lung Cancer: New Insights from Matrix...
Molecular Inverse Comorbidity between Alzheimer's Disease and Lung Cancer: New Insights from Matrix Factorization12mby Alessandro Greco via International Journal of Molecular SciencesIJMS, Vol. 20, Pages 3114: Molecular Inverse Comorbidity between Alzheimer's Disease and Lung Cancer: New Insights from Matrix FactorizationInternational Journal of Molecular Sciences doi: 10.3390/ijms20133114Authors: Alessandro Greco Jon Sanchez Valle Vera Pancaldi Anaïs Baudot Emmanuel Barillot Michele Caselle Alfonso...
Αλέξανδρος Γ. Σφακιανάκης
15m
Addictive Behaviors
The therapeutic role of emotion regulation and coping strategies during a stand-alone DBT Skills training program for alcohol use disorder and concurrent substance use disordersPublication date: Available online 25 June 2019Source: Addictive BehaviorsAuthor(s): Marco Cavicchioli, Mariagrazia Movalli, Giulia Vassena, Pietro Ramella, Francesca Prudenziati, Cesare MaffeiAbstractClinical trials on Dialectical Behavior Therapy Skills Training (DBT-ST) as a stand-alone intervention for alcohol use disorder...
Αλέξανδρος Γ. Σφακιανάκης
16m
Journal of Cranio-Maxillofacial Surgery, Use of CAD-CAM technology to improve orthognathic surgery...
Journal of Cranio-Maxillofacial Surgery,Use of CAD-CAM technology to improve orthognathic surgery outcomes in patients with severe obstructive sleep apnoea syndromePublication date: Available online 25 June 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Diego sergio rossi, Michele romano, Ahmed Hassan Sweed, Alessandro Baj, Aldo bruno Gianni, Giada Anna BeltraminiAbstractIntroductionAlthough multilevel surgery is the mainstay treatment for severe obstructive sleep apnoea syndrome (OSAS),...
Αλέξανδρος Γ. Σφακιανάκης
17m
Talanta, A fully derivatized 4-chlorophenylcarbamate-β-cyclodextrin bonded chiral stationary...
Talanta,A fully derivatized 4-chlorophenylcarbamate-β-cyclodextrin bonded chiral stationary phase for enhanced enantioseparation in HPLCPublication date: 1 November 2019Source: Talanta, Volume 204Author(s): Jiayi Sun, Siman Ma, Beibei Liu, Jia Yu, Xingjie GuoAbstractThis paper reports an effective approach for the fabrication of a per-4-chlorophenylcarbamate-β-cyclodextrin (β-CD) bonded chiral stationary phase (CPCDP) in high-performance liquid chromatography. The morphology and structure of the...
Αλέξανδρος Γ. Σφακιανάκης
18m
Cancers, Cancers, Vol. 11, Pages 888: Exo-miRNAs as a New Tool for Liquid Biopsy in Lung Cancer...
Cancers,Cancers, Vol. 11, Pages 888: Exo-miRNAs as a New Tool for Liquid Biopsy in Lung CancerCancers, Vol. 11, Pages 888: Exo-miRNAs as a New Tool for Liquid Biopsy in Lung CancerCancers doi: 10.3390/cancers11060888Authors:Orazio FortunatoPatrizia GaspariniMattia BoeriGabriella SozziLung cancer is the predominant cause of cancer-related deaths. The high mortality rates are mainly due to the lack of diagnosis before the cancer is at a late stage. Liquid biopsy is a promising technique that could...
Αλέξανδρος Γ. Σφακιανάκης
19m
Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation...
Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs16hby Mastio, J., Condamine, T., Dominguez, G., Kossenkov, A. V., Donthireddy, L., Veglia, F., Lin, C., Wang, F., Fu, S., Zhou, J., Viatour, P., Lavilla-Alonso, S., Polo, A. T., Tcyganov, E. N., Mulligan, C., Nam, B., Bennett, J., Masters, G., Guarino, M., Kumar, A., Nefedova, Y., Vonderheide, R. H., Languino, L. R., Abrams, S. I., Gabrilovich, D. I. via Latest ArticlesMastio et al. describe...
Αλέξανδρος Γ. Σφακιανάκης
20m
Radiation dosimetry of [ 18 F]-PSS232—a PET radioligand for imaging mGlu5 receptors in humans 16h...
Radiation dosimetry of [ 18 F]-PSS232—a PET radioligand for imaging mGlu5 receptors in humans16hvia http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=13550&channel-name=EJNMMI+ResearchAbstractPurpose(E)-3-(pyridin-2-ylethynyl)cyclohex-2-enone O-(3-(2-[18F]-fluoroethoxy)propyl) oxime ([18F]-PSS232) is a new PET tracer for imaging of metabotropic glutamate receptor subtype 5 (mGlu5), and has shown promising results in rodents and humans. The aim of this study was...
Αλέξανδρος Γ. Σφακιανάκης
20m
The Journal of Steroid Biochemistry and Molecular Biology, Vitamin D fortification of foods in...
The Journal of Steroid Biochemistry and Molecular Biology,Vitamin D fortification of foods in India: present and past scenarioPublication date: Available online 24 June 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Yasmeena Jan, Muneeb Malik, Mifftha Yaseen, Sayeed Ahmad, Mohammed Imran, Suhail Rasool, Afrozul HaqAbstractIndia is a densely populated country known for its traditional, cultural and lingual diversity. In India Deficiency of vitamin D is seen in both...
Αλέξανδρος Γ. Σφακιανάκης
20m
Journal of the Academy of Nutrition and Dietetics, Diet Quality among the Brazilian Population...
Journal of the Academy of Nutrition and Dietetics,Diet Quality among the Brazilian Population and Associated Socioeconomic and Demographic Factors: Analysis from the National Dietary Survey 2008-2009Publication date: Available online 24 June 2019Source: Journal of the Academy of Nutrition and DieteticsAuthor(s): Juliana de Paula Matos Souza, Manuela Magela de Lima, Paula Martins HortaAbstractBackgroundEvaluating diet quality is a way to monitor a population's adherence to dietary guidelines.ObjectiveTo...
Αλέξανδρος Γ. Σφακιανάκης
21m
Annals of Allergy, Asthma & Immunology, Exhaled nitric oxide as a marker of chlorine exposure...
Annals of Allergy, Asthma & Immunology,Exhaled nitric oxide as a marker of chlorine exposure in young asthmatic swimmersPublication date: Available online 25 June 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Ourania S. Kotsiou, Sotiria Peletidou, George Vavougios, Eleni Karetsi, Vasileios Stavrou, George Zakynthinos, Konstantinos I. Gourgoulianis, Zoe DaniilScienceDirect Publication: Annals of Allergy, Asthma & Immunology16hAllergy WatchPublication date: Available online...
Αλέξανδρος Γ. Σφακιανάκης
21m
Vaccine, A multi-epitope DNA vaccine co-administered with monophosphoryl lipid A adjuvant provides...
Vaccine,A multi-epitope DNA vaccine co-administered with monophosphoryl lipid A adjuvant provides protection against tick transmitted <em>Ehrlichia ruminantium</em> in sheepPublication date: Available online 25 June 2019Source: VaccineAuthor(s): S.I. Tshilwane, N. Thema, H.C. Steyn, M. van Kleef, A. PretoriusAbstractPreviously, a heartwater experimental DNA vaccine provided 100% protection following laboratory challenge with Ehrlichia ruminantium administered by needle but not against...
Αλέξανδρος Γ. Σφακιανάκης
22m
Virologica Sinica, Seroprevalence of Severe Fever with Thrombocytopenia Syndrome Phlebovirus...
Virologica Sinica,Seroprevalence of Severe Fever with Thrombocytopenia Syndrome Phlebovirus in Domesticated Deer in South KoreaAbstract Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) has a wide host range. Not only has it been found in humans, but also in many wild and domesticated animals. The infection of breeding deer on farms is a particularly worrisome public health concern due to the large amount of human contact and the diverse use of deer products, including raw blood. To...
Αλέξανδρος Γ. Σφακιανάκης
23m
Peptides, Protective effect of PACAP-38 on retinal pigmented epithelium in an <em>in...
Peptides,Protective effect of PACAP-38 on retinal pigmented epithelium in an <em>in vitro</em> and <em>in vivo</em> model of diabetic retinopathy through EGFR-dependent mechanismPublication date: Available online 24 June 2019Source: PeptidesAuthor(s): Grazia Maugeri, Agata Grazia D'Amico, Claudio Bucolo, Velia D'AgataAbstractDiabetic retinopathy (DR) is one of the most common microvascular complications of diabetes.In the last years, several in vivo studies have demonstrated...
Αλέξανδρος Γ. Σφακιανάκης
23m
Allergy and Clinical Immunology, Ambient Air Pollution, Asthma Drug Response and Telomere Length...
Allergy and Clinical Immunology,Ambient Air Pollution, Asthma Drug Response and Telomere Length in African American YouthPublication date: Available online 24 June 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Eunice Y. Lee, Sam S. Oh, Marquitta J. White, Celeste S. Eng, Jennifer R. Elhawary, Luisa N. Borrell, Thomas J. Nuckton, Andrew M. Zeiger, Kevin L. Keys, Angel C.Y. Mak, Donglei Hu, Scott Huntsman, Maria G. Contreras, Lesly-Anne Samedy, Pagé C. Goddard, Sandra L. Salazar,...
Αλέξανδρος Γ. Σφακιανάκης
24m
Archives of Physical Medicine and Rehabilitation, Editors' Selections From This Issue: Volume...
Archives of Physical Medicine and Rehabilitation,Editors' Selections From This Issue: Volume 100 / Number 7 / July 2019Publication date: July 2019Source: Archives of Physical Medicine and Rehabilitation, Volume 100, Issue 7Author(s):Archives of Physical Medicine and Rehabilitation16h"A Huge, Life-Changing Thing:" A Qualitative Survey of the Priorities and Goals of Young Stroke SurvivorsPublication date: July 2019Source: Archives of Physical Medicine and Rehabilitation, Volume 100, Issue 7Author(s):...
Αλέξανδρος Γ. Σφακιανάκης
25m
Evidence-Based Complementary and Alternative Medicine, Efficacy and Safety of Fire Needle Therapy...
Evidence-Based Complementary and Alternative Medicine,Efficacy and Safety of Fire Needle Therapy for Nodular Prurigo: A Quantitative StudyIn this quantitative study, we evaluated the effectiveness and safety of fire needle therapy for nodular prurigo. We systematically searched several databases, including EMBASE, PubMed, the Cochrane Library, the Web of Science, the China Network Knowledge Infrastructure, the Wanfang Data Knowledge Service Platform, and the China Science and Technology Journal Database,...
Αλέξανδρος Γ. Σφακιανάκης
25m
Data in Brief, Data related to anaerobic digestion of bioplastics: Images and properties of digested...
Data in Brief,Data related to anaerobic digestion of bioplastics: Images and properties of digested bioplastics and digestate, synthetic food waste recipe and packaging informationPublication date: August 2019Source: Data in Brief, Volume 25Author(s): Wei Zhang, Francisco Torrella, Charles J. Banks, Sonia HeavenAbstractThe data presented in this article are related to the research article entitled 'Degradation of some EN13432 compliant plastics in simulated mesophilic anaerobic digestion of food...
Αλέξανδρος Γ. Σφακιανάκης
26m
Defining specific allergens for improved component-resolved diagnosis of shrimp allergy in adults ...
Defining specific allergens for improved component-resolved diagnosis of shrimp allergy in adults15hvia ScienceDirect Publication: Molecular ImmunologyPublication date: August 2019Source: Molecular Immunology, Volume 112Author(s): Elecia B. Johnston, Sandip D. Kamath, Swati P. Iyer, Kunal Pratap, Shaymaviswanathan Karnaneedi, Aya C. Taki, Roni Nugraha, Patrick M. Schaeffer, Jennifer M. Rolland, Robyn E. O'Hehir, Andreas L. LopataAbstractShrimp is one of the predominant causes of food allergy among...
Αλέξανδρος Γ. Σφακιανάκης
26m
Clinical Neurology and Neurosurgery, Disturbance of Thiol/disulfide Aminothiols Homeostasis...
Clinical Neurology and Neurosurgery,Disturbance of Thiol/disulfide Aminothiols Homeostasis in Patients with Acute Ischemic Stroke Stroke:Preliminary findingsPublication date: Available online 24 June 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Marina Yurievna Maksimova, Alexander Vladimirovich Ivanov, Edward Danielevich Virus, Valery Vasil'evich Alexandrin, Ksenya Alexandrovna Nikiforova, Polina Olegovna Bulgakova, Fatima Ramazanovna Ochtova, Ekaterina Taymurazovna Suanova, Mikhail...
Αλέξανδρος Γ. Σφακιανάκης
26m
Microbial Drug Resistance, Phenotypic and Genotypic Characterization of Carbapenem-Resistant...
Microbial Drug Resistance,Phenotypic and Genotypic Characterization of Carbapenem-Resistant Gram-Negative Bacilli Pathogens from Hospitals in GhanaMicrobial Drug Resistance, Ahead of Print.Microbial Drug Resistance - Table of Contents15hComparative Proteomics of Methicillin-Resistant Staphylococcus aureus Subjected to Synergistic Effects of the Lantibiotic Nisin and OxacillinMicrobial Drug Resistance, Ahead of Print.Microbial Drug Resistance - Table of Contents15h
Αλέξανδρος Γ. Σφακιανάκης
26m
Why and how music can be used to rehabilitate and develop speech and language skills in hearing-impaired...
Why and how music can be used to rehabilitate and develop speech and language skills in hearing-impaired children15hvia Hearing ResearchPublication date: Available online 25 June 2019Source: Hearing ResearchAuthor(s): Ritva Torppa, Minna HuotilainenAbstractThis paper presents evidence for a strong connection between the development of speech and language skills and musical activities of children and adolescents with hearing impairment and/or cochlear implants. This conclusion is partially based on...
Αλέξανδρος Γ. Σφακιανάκης
27m
American Journal of Otolaryngology, Evaluation of the quality of life in adults with cochlear...
American Journal of Otolaryngology,Evaluation of the quality of life in adults with cochlear implants: As good as the healthy adults?Publication date: Available online 24 June 2019Source: American Journal of OtolaryngologyAuthor(s): Elif Tuğba Saraç, Merve Ozbal Batuk, Gonca SennarogluAbstractPurposeThe aim of this study was to compare the quality of life (QoL) of adult CI users with the QoL of adults in the healthy and normal-hearing population.Materials and methods31 patients with CIs were included...
Αλέξανδρος Γ. Σφακιανάκης
28m
The role of receptor MAS in microglia-driven retinal vascular development 15h via http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=10456&channel-name=Angiogenesis...
The role of receptor MAS in microglia-driven retinal vascular development15hvia http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=10456&channel-name=AngiogenesisAbstractObjectiveThe receptor MAS, encoded by Mas1, is expressed in microglia and its activation has been linked to anti-inflammatory actions. However, microglia are involved in several different processes in the central nervous system, including the promotion of angiogenesis. We therefore hypothesized...
Αλέξανδρος Γ. Σφακιανάκης
28m
Subacute vessel wall imaging at 7-T MRI in post-thrombectomy stroke patients 15h via Neuroradiology...
Subacute vessel wall imaging at 7-T MRI in post-thrombectomy stroke patients15hvia NeuroradiologyAbstractPurposeReports from 3-T vessel wall MRI imaging have shown contrast enhancement following thrombectomy for acute stroke, suggesting potential intimal damage. Comparisons have shown higher SNR and more lesions detected by vessel wall imaging when using 7 T compared with 3 T. The aim of this study was to investigate the vessel walls after stent retriever thrombectomy using high-resolution vessel...
Αλέξανδρος Γ. Σφακιανάκης
28m
A large scale meta analysis identifies common adverse events with checkpoint inhibitors vs chemotherapy...
A large scale meta analysis identifies common adverse events with checkpoint inhibitors vs chemotherapy in melanoma patients15hvia ScienceDirect Publication: International ImmunopharmacologyPublication date: September 2019Source: International Immunopharmacology, Volume 74Author(s): Ruyi Zhang, Xuehui Li, Zhiyu You, Li Jiang, Yaguang Weng, Qiong Shi, Lin Du, Shujuan YanAbstractBackgroundA meta-analysis was performed to assess the risk of common adverse events in melanoma patients treated with checkpoint...
Αλέξανδρος Γ. Σφακιανάκης
29m
Presence of sialic acids in bronchioloalveolar cells and identification and quantification of <em>N</em>-acetylneuraminic...
Presence of sialic acids in bronchioloalveolar cells and identification and quantification of <em>N</em>-acetylneuraminic and <em>N</em>-glycolylneuraminic acids in the lung15hvia Acta HistochemicaPublication date: Available online 24 June 2019Source: Acta HistochemicaAuthor(s): Maria de Fátima Martins, Ana Honório-Ferreira, Paula Martins, Carlos Alberto GonçalvesAbstractThe lung, in air-breathing vertebrates, is a tree-like structure composed of branching tubes ending in...
Αλέξανδρος Γ. Σφακιανάκης
29m
Journal of Autoimmunity, Ultraviolet light induces increased T cell activation in lupus-prone...
Journal of Autoimmunity,Ultraviolet light induces increased T cell activation in lupus-prone mice via type I IFN-dependent inhibition of T regulatory cellsPublication date: Available online 24 June 2019Source: Journal of AutoimmunityAuthor(s): Sonya J. Wolf, Shannon N. Estadt, Jonathan Theros, Tyson Moore, Jason Ellis, Jianhua Liu, Tamra J. Reed, Chaim O. Jacob, Johann E. Gudjonsson, J. Michelle KahlenbergAbstractUltraviolet (UV) light is a known trigger of skin and possibly systemic inflammation...
Αλέξανδρος Γ. Σφακιανάκης
29m
European Journal of Surgical Oncology (EJSO), A systematic review of risk-reducing cancer surgery...
European Journal of Surgical Oncology (EJSO),A systematic review of risk-reducing cancer surgery outcomes for hereditary cancer syndromesPublication date: Available online 25 June 2019Source: European Journal of Surgical OncologyAuthor(s): Oliver Peacock, Peadar S. Waters, Jaime Otero de Pablos, Alex Boussioutas, Anita Skandarajah, Jonathan A. Simpson, Satish K. Warrier, Alexander G. HeriotAbstractCancer predisposition genes are rare mutations that confer a high risk of cancer. For many hereditary...
Αλέξανδρος Γ. Σφακιανάκης
30m
Amino Acids, Synthetic peptide-labelled micelles for active targeting of cells overexpressing...
Amino Acids,Synthetic peptide-labelled micelles for active targeting of cells overexpressing EGF receptorsAbstract The goal of nanomedicine is to transport drugs to pathological tissues, reducing side effects while increasing targeting and efficacy. Aggregates grafted by bioactive molecules act as the active targeting agents. Among bioactive molecules, peptides, which are able to recognize overexpressed receptors on cancer cell membranes, appear to be very promising. The aim of this study was to...
Αλέξανδρος Γ. Σφακιανάκης
30m
 The Scientific World Journal The HLA-Cw12 Allele Is an Important Susceptibility Allele for Psoriasis...
 The Scientific World JournalThe HLA-Cw12 Allele Is an Important Susceptibility Allele for Psoriasis and Is Associated with Resistant Psoriasis in the Turkish PopulationBackground. Psoriasis is a multifactorial immune-mediated inflammatory disease triggered by both genetic and environmental factors. The strong association between psoriasis and HLA-C06 allele has been demonstrated in various races. The HLA-C12 allele is closely related to the HLA-C06 family of alleles and shares identical sequences....
Αλέξανδρος Γ. Σφακιανάκης
31m
 World Neurosurgery Robot-assisted pedicle screw placement is safe and accurate in both experienced...
 World NeurosurgeryRobot-assisted pedicle screw placement is safe and accurate in both experienced and two supervised, in-training surgeonsPublication date: Available online 25 June 2019Source: World NeurosurgeryAuthor(s): Mehdi I. Siddiqui, David J. Wallace, Luis M. Salazar, Arnold B. VardimanAbstractObjectivesTo describe the learning curve of pedicle screw placement using Robot-Assisted Spine Surgery (RASS) of an experienced neurosurgeon and two supervised neurosurgical fellows.MethodsThe first...
Αλέξανδρος Γ. Σφακιανάκης
31m
BioMed Research International, Neutrophil-to-Lymphocyte Ratio in Ovarian Cancer Patients with...
BioMed Research International,Neutrophil-to-Lymphocyte Ratio in Ovarian Cancer Patients with Low CA125 ConcentrationOvarian cancer cases with low CA125 concentration are problematic and increase the high false negative results ratio during routine physical examination testing. Unfortunately, patients without early discovery have very low survival rates. In our study, we investigated the possible role of differential leukocyte counts and the neutrophil-to-lymphocyte ratio (NLR) in ovarian cancer patients...
Αλέξανδρος Γ. Σφακιανάκης
32m
 ScienceDirect Publication: Oral Oncology, Induction chemotherapy in head and neck cancers:...
 ScienceDirect Publication: Oral Oncology,Induction chemotherapy in head and neck cancers: Results and controversiesPublication date: August 2019Source: Oral Oncology, Volume 95Author(s): Max Gau, Andy Karabajakian, Thibaut Reverdy, Eve-Marie Neidhardt, Jérôme FayetteAbstractStandard treatment for locally advanced head and neck squamous cell carcinoma (LAHNSCC) consists mainly of concurrent chemoradiation (CCR) but induction chemotherapy (IC) by docetaxel-cisplatin-fluorouracil (TPF), followed by...
Αλέξανδρος Γ. Σφακιανάκης
32m
Oral and Maxillofacial Surgery, Lifelong learning A higher order of consciousness and a construct...
Oral and Maxillofacial Surgery,Lifelong learning A higher order of consciousness and a construct for faculty developmentPublication date: Available online 24 June 2019Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Eric R. CarlsonAbstractLearning is an element of human personal and professional development that occurs throughout life in a variety of informal and formal contexts. Meaning making, a process in which people construct meaning of events and experiences that are part of and...
Αλέξανδρος Γ. Σφακιανάκης
33m
 British Journal of Oral and Maxillofacial Surgery, An alternative suture technique for vein...
 British Journal of Oral and Maxillofacial Surgery,An alternative suture technique for vein diameter's discrepancy anastomosisPublication date: Available online 24 June 2019Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): R. Rauso, G. Colella, L. Rugge, F. Chirico, G. TartaroBritish Journal of Oral and Maxillofacial Surgery14h
Αλέξανδρος Γ. Σφακιανάκης
33m
FEMS Microbiology Letters
Role of Research Educator in sequential course-based undergraduate research experience programABSTRACTIn our First-Year Research Immersion (FRI) program, students take a sequence of three CUREs (course-based undergraduate research experiences). Each Research Educator (Research Assistant Professor, aka RE) oversees the day-to-day work of about 30 first-year and 25 second-year students in a dedicated research-training lab. Instead of the typical work-load division for faculty between their teaching...
Αλέξανδρος Γ. Σφακιανάκης
34m
Medgadget, Women Paint Over Own Avatars to Improve Mental Health How we view our bodies is...
Medgadget,Women Paint Over Own Avatars to Improve Mental HealthHow we view our bodies is often influenced by popular culture and each one of our's social environment. Young women, in particular, tend to suffer from poor "body image," which can result in depression, eating disorders, and all kinds of other mental issues. Researchers at the University of Missouri wanted to see whether letting women view their own bodies from a different, more abstract perspective can influence their own body image...
Αλέξανδρος Γ. Σφακιανάκης
35m
Journal for ImmunoTherapy of Cancer, Comparative safety and efficacy of anti-PD-1 monotherapy,...
Journal for ImmunoTherapy of Cancer,Comparative safety and efficacy of anti-PD-1 monotherapy, chemotherapy alone, and their combination therapy in advanced nasopharyngeal carcinoma: findings from recent advances in landmark trialsAbstract Recent phase 1–2 trials reported manageable safety profiles and promising antitumor activities of anti-PD-1 drugs (pembrolizumab, nivolumab, camrelizumab and JS001) with/without chemotherapy in recurrent/metastatic nasopharyngeal carcinoma (RM-NPC), however head-to-head...
Αλέξανδρος Γ. Σφακιανάκης
36m
 Journal of Interferon & Cytokine Research, RNA Helicase LGP2 Negatively Regulates RIG-I...
 Journal of Interferon & Cytokine Research,RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain UbiquitinationJournal of Interferon &Cytokine Research, Ahead of Print.Journal of Interferon & Cytokine Research - Table of Contents14h
Αλέξανδρος Γ. Σφακιανάκης
37m
Der Pathologe, Rundzellige Sarkome Zusammenfassung Rundzellige Sarkome sind hochmaligne Tumoren,...
Der Pathologe,Rundzellige SarkomeZusammenfassung Rundzellige Sarkome sind hochmaligne Tumoren, die insbesondere bei Kindern, Jugendlichen und jungen Erwachsenen vorkommen. Sie werden durch rekurrente Translokationen unter Beteiligung von Transkriptionsfaktoren verursacht. Typische Vertreter sind das Ewing-Sarkom, Ewing-artige Sarkome (z. B. CIC-DUX4- und BCOR-Sarkome), der desmoplastische klein-rundzellige Tumor (DSRCT) und das alveoläre Rhabdomyosarkom (ARMS). Die einzelnen Entitäten unterscheiden...
Αλέξανδρος Γ. Σφακιανάκης
37m
Medical Hypotheses, Post traumatic retinal injuries: Does the ocular protective reflex play...
Medical Hypotheses,Post traumatic retinal injuries: Does the ocular protective reflex play a crucial role?Publication date: Available online 24 June 2019Source: Medical HypothesesAuthor(s): Amar Pujari, Rohan Chawla, Harathy Selvan, Ritika Mukhija, Atul KumarAbstractTraumatic retinal injuries are commonly encountered in most retinal subspecialty clinics. Retinal dialysis, detachment and other complications consequent to blunt trauma are often thought to be due to equatorial expansion of the globe...
Αλέξανδρος Γ. Σφακιανάκης
38m
Der Chirurg, Interventionelle Versorgung tracheo-/bronchoösophagealer Fisteln Zusammenfassung...
Der Chirurg,Interventionelle Versorgung tracheo-/bronchoösophagealer FistelnZusammenfassung Erworbene Fisteln zwischen dem Ösophagus und den Atemwegen werden in benigne und maligne tracheoösophageale Fisteln unterteilt. Es stehen operative und endoskopische Therapieoptionen zur Verfügung. Das endoskopische Therapieverfahren der Wahl ist die Stentimplantation. Endoskopische Stents werden nach dem zur Herstellung verwendeten Material in Silikonstents und selbstexpandierende Metallstents (SEMS) unterteilt....
Αλέξανδρος Γ. Σφακιανάκης
38m
Coping strategies among immigrant women who have experienced intimate partner violence in North America:...
Coping strategies among immigrant women who have experienced intimate partner violence in North America: A narrative review14hvia http://rss.sciencedirect.com/publication/science/13591789Publication date: Available online 25 June 2019Source: Aggression and Violent BehaviorAuthor(s): Burcu Ozturk, Qingyi Li, David L. AlbrightAbstractIntimate partner violence (IPV) is experienced in every society. IPV can cause severe mental, physical, social, and economic consequences for survivors, and impact their...
Αλέξανδρος Γ. Σφακιανάκης
38m
Rejuvenation Research, Will Repeated Ablative Er:YAG Laser Treatment Sessions Cause Facial Skin...
Rejuvenation Research,Will Repeated Ablative Er:YAG Laser Treatment Sessions Cause Facial Skin Sensitivity? Results of a 12-Month, Prospective, Randomized Split-Face StudyRejuvenation Research, Ahead of Print.Rejuvenation Research14h
Αλέξανδρος Γ. Σφακιανάκης
39m
Allergology International, Cysteinyl leukotriene metabolism of human eosinophils in allergic...
Allergology International,Cysteinyl leukotriene metabolism of human eosinophils in allergic diseasePublication date: Available online 24 June 2019Source: Allergology InternationalAuthor(s): Jun Miyata, Koichi Fukunaga, Yusuke Kawashima, Osamu Ohara, Makoto AritaAbstractEosinophils are multifaceted immune cells with diverse functions that enhance allergic inflammation. Cysteinyl leukotrienes (cys-LTs), mainly synthesized in eosinophils, are a class of inflammatory lipid mediators produced via multiple...
Αλέξανδρος Γ. Σφακιανάκης
39m
Cognitive Science, Interpreting Silent Gesture: Cognitive Biases and Rational Inference in Emerging...
Cognitive Science,Interpreting Silent Gesture: Cognitive Biases and Rational Inference in Emerging Language SystemsAbstract Natural languages make prolific use of conventional constituent‐ordering patterns to indicate "who did what to whom," yet the mechanisms through which these regularities arise are not well understood. A series of recent experiments demonstrates that, when prompted to express meanings through silent gesture, people bypass native language conventions, revealing apparent biases...
Αλέξανδρος Γ. Σφακιανάκης
40m
Journal of NeuroInterventional Surgery, Mechanical thrombectomy for basilar artery occlusion:...
Journal of NeuroInterventional Surgery,Mechanical thrombectomy for basilar artery occlusion: efficacy, outcomes, and futile recanalization in comparison with the anterior circulationBackgroundPerforming mechanical thrombectomy (MT) in patients with basilar artery occlusion (BAO) is currently not evidence-based.ObjectiveTo compare patients' outcome, relative merits of achieving recanalization, and predictors of futile recanalization (FR) between BAO and anterior circulation large vessel occlusion...
Αλέξανδρος Γ. Σφακιανάκης
40m
Analytical Chemistry, [ASAP] 3D Printed Liquid Cooling Interface for a Deep-UV-LED-Based Flow-Through...
Analytical Chemistry,[ASAP] 3D Printed Liquid Cooling Interface for a Deep-UV-LED-Based Flow-Through Absorbance DetectorAnalytical ChemistryDOI: 10.1021/acs.analchem.9b01335Analytical Chemistry13h[ASAP] Ultrasensitive Detection of DNA via SI-eRAFT and in Situ Metalization Dual-Signal AmplificationAnalytical ChemistryDOI: 10.1021/acs.analchem.9b01961Analytical Chemistry13h[ASAP] All Ion Differential Analysis Refines the Detection of Terminal and Internal Diagnostic Fragment Ions for the Characterization...
Αλέξανδρος Γ. Σφακιανάκης
41m
Quantitative Evaluation of Lobar Pulmonary Function of Emphysema Patients with Endobronchial Coils...
Quantitative Evaluation of Lobar Pulmonary Function of Emphysema Patients with Endobronchial Coils13hby S.Karger AG via RespirationBackground: Recent advances in bronchoscopic lung volume reduction offer new therapies for patients with emphysema and hyperinflation. Pulmonary lobe segmentation with quantification of lobar volumes and emphysema severity plays a pivotal role in treatment planning and post-interventional assessment. Computed tomography (CT)-derived lobar volumes could reflect more accurate...
Αλέξανδρος Γ. Σφακιανάκης
42m
Autoimmune Epilepsy 13h via Latest Results for Neurotherapeutics AbstractThe field of autoimmune...
Autoimmune Epilepsy13hvia Latest Results for NeurotherapeuticsAbstractThe field of autoimmune epilepsy has evolved substantially in the last few decades with discovery of several neural autoantibodies and improved mechanistic understanding of these immune-mediated syndromes. A considerable proportion of patients with epilepsy of unknown etiology have been demonstrated to have an autoimmune cause. The majority of the patients with autoimmune epilepsy usually present with new-onset refractory seizures...
Αλέξανδρος Γ. Σφακιανάκης
42m
Journal of Materials Science, Synthesis of cyclic carbonate by CO 2 fixation to epoxides using...
Journal of Materials Science,Synthesis of cyclic carbonate by CO 2 fixation to epoxides using interpenetrated MOF-5/ n -Bu 4 NBrAbstract Phase-pure interpenetrated MOF-5 ([Zn4(O)(BDC)3]) was synthesized by pH* control in a reaction medium, and its stability in the presence of epoxides was confirmed by powder X-ray diffraction analysis. Interpenetrated MOF-5/tetra-n-butylammonium bromide (int-MOF-5/n-Bu4NBr) showed a high catalytic activity toward CO2 fixation to epoxide to synthesize cyclic carbonates....
Αλέξανδρος Γ. Σφακιανάκης
43m
Brain - Advance Access, Parallel pathways of seizure generalization AbstractGeneralized convulsive...
Brain - Advance Access,Parallel pathways of seizure generalizationAbstractGeneralized convulsive status epilepticus is a life-threatening emergency, because recurrent convulsions can cause death or injury. A common form of generalized convulsive status epilepticus is of focal onset. The neuronal circuits activated during seizure spread from the hippocampus, a frequent site of seizure origin, to the bilateral motor cortex, which mediates convulsive seizures, have not been delineated. Status epilepticus...
Αλέξανδρος Γ. Σφακιανάκης
44m
Drug Delivery and Translational Research, Anti-pollution cosmetic-based one-step formation of...
Drug Delivery and Translational Research,Anti-pollution cosmetic-based one-step formation of w/o/w multiple emulsion containing D-biotin for skin protection: fabrication and in vitro and in vivo evaluationAbstract Continuous contact of air pollutants on human skin has produced early ageing and led to roughness, dryness, poor elasticity, increased wrinkling and irregular pigmentation of the skin. The present study was carried out to fabricate an anti-pollution cosmetic-based w/o/w multiple emulsion...
Αλέξανδρος Γ. Σφακιανάκης
44m
Shaft Function of Kinesin-1's α4 Helix in the Processive Movement 10h via Latest Results for...
Shaft Function of Kinesin-1's α4 Helix in the Processive Movement10hvia Latest Results for Cellular and Molecular BioengineeringAbstractIntroductionKinesin-1 motor is a molecular walking machine constructed with amino acids. The understanding of how those structural elements play their mechanical roles is the key to the understanding of kinesin-1 mechanism.MethodsUsing molecular dynamics simulations, we investigate the role of a helix structure, α4 (also called switch-II helix), of kinesin-1's motor...
Αλέξανδρος Γ. Σφακιανάκης
50m
Journal of Nanoparticle Research, Comparison of biological markers in aerosol-weighed workplaces...
Journal of Nanoparticle Research,Comparison of biological markers in aerosol-weighed workplacesAbstract Airborne particulates present a potential hazard to health in a variety of indoor workplaces, from offices to the manufacturing floor. Dust and aerosols are two of the most common occupational risk factors in the workplace worldwide. It is very important to understand when it is sufficient to describe dust exposure only by given mass concentration that dust particles could be in the nanosized range...
Αλέξανδρος Γ. Σφακιανάκης
52m
Herald Cell: The Gateway to Posterior Tympanotomy—A Cadaveric Study 4m via Otolaryngology Indian...
Herald Cell: The Gateway to Posterior Tympanotomy—A Cadaveric Study4mvia Otolaryngology IndianAbstractPosterior tympanotomy is the avenue to the facial recess of the middle ear from mastoid antrum. The entry into the facial recess in many cases is heralded by a distinct air cell before approaching the facial-chordal plane. The current study was undertaken to determine the prevalence of this 'Herald Cell' in an adult cadaveric population. It was a human cadaveric temporal bone dissection study. The...
Αλέξανδρος Γ. Σφακιανάκης
54m
Clinical Cancer Research Online First Articles, Nivolumab in Patients With Recurrent or Metastatic...
Clinical Cancer Research Online First Articles,Nivolumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: Efficacy and Safety in CheckMate 141 by Prior Cetuximab UsePurpose: Cetuximab, which modulates immune responses, may affect the efficacy of subsequent immunotherapy. Here, we assessed outcomes with nivolumab, by prior cetuximab exposure, in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) who had experienced...
Αλέξανδρος Γ. Σφακιανάκης
56m
Sleep and Breathing, The association of OSAS and uvula: the role of MRI in this egg-chicken problem...
Sleep and Breathing,The association of OSAS and uvula: the role of MRI in this egg-chicken problem in OSASAbstract Purpose Obstructive sleep apnea syndrome (OSAS) is a condition resulting from repetitive partial or complete upper airway obstruction, and its etiology remains uncertain. Polysomnography is the gold standard diagnostic test for OSAS. However, there are long wait times for this evaluation, so questionnaires or ancillary diagnostic methods are used to select appropriate patients. One of...
Αλέξανδρος Γ. Σφακιανάκης
56m
Investigational New Drugs, A randomized phase 2 trial of the efficacy and safety of a novel topical...
Investigational New Drugs,A randomized phase 2 trial of the efficacy and safety of a novel topical povidone-iodine formulation for Cancer therapy-associated ParonychiaSummary Purpose Cancer therapy-associated paronychia (CAP) is a frequent adverse event associated with cytotoxic and targeted therapies that may impact dosing of anticancer therapies and patient quality of life (QoL). There are currently no evidence-based management strategies or approved treatments for CAP. Materials and Methods This...
Αλέξανδρος Γ. Σφακιανάκης
57m
BMC Infectious Diseases, Frequency of the Mycobacterium tuberculosis RDRio genotype and its association...
BMC Infectious Diseases,Frequency of the Mycobacterium tuberculosis RDRio genotype and its association with multidrug-resistant tuberculosisIn recent decades, Mycobacterium tuberculosis with the RDRio genotype, frequently isolated from tuberculosis patients in Rio de Janeiro, has become part of the Latin American – Mediterranean (LAM) family and has ...BMC Infectious Diseases - Latest Articles2hClusterization of co-morbidities and multi-morbidities among persons living with HIV: a cross-sectional...
Αλέξανδρος Γ. Σφακιανάκης
57m
 International Journal of Molecular Sciences, IJMS, Vol. 20, Pages 3113: Immortalized Human hTert/KER-CT...
 International Journal of Molecular Sciences,IJMS, Vol. 20, Pages 3113: Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus VulgarisIJMS, Vol. 20, Pages 3113: Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris International Journal of Molecular Sciences doi: 10.3390/ijms20133113 Authors: Benedikt Beckert Francesca Panico Robert Pollmann Rüdiger...
Αλέξανδρος Γ. Σφακιανάκης
58m
BMJ Case Reports, Multiple sites acquired lipodystrophy in two siblings: a rare adverse effect...
BMJ Case Reports,Multiple sites acquired lipodystrophy in two siblings: a rare adverse effect of intramuscular triamcinoloneBMJ Case Reports Last 6 Issues1hRare case of Bing-Neel syndrome treated successfully with ibrutinibWaldenstrom's macroglobulinaemia (WM) is a lymphoproliferative disorder of the B cell origin. It is characterised by the presence of IgM paraprotein in the serum and lymphoplasmacytic lymphoma cells in the bone marrow with extranodal involvement relatively uncommon. Bing-Neel syndrome...
Αλέξανδρος Γ. Σφακιανάκης
59m
 Future Oncology, Anti-PD-1 versus anti-PD-L1 therapy in patients with pretreated advanced non-small-cell...
 Future Oncology,Anti-PD-1 versus anti-PD-L1 therapy in patients with pretreated advanced non-small-cell lung cancer: a meta-analysisFuture Oncology, Ahead of Print.Future Oncology1hExcess of second tumors in denosumab-treated patients: a metabolic hypothesisFuture Oncology, Ahead of Print.Future Oncology1hPrognostic impact of tumor-associated macrophage infiltration in esophageal cancer: a meta-analysisFuture Oncology, Ahead of Print.Future Oncology1hPreoperative high c-reactive protein/albumin...
Αλέξανδρος Γ. Σφακιανάκης
1h
BMJ Open recent issues, DONORS (Donation Network to Optimise Organ Recovery Study): Study protocol...
BMJ Open recent issues,DONORS (Donation Network to Optimise Organ Recovery Study): Study protocol to evaluate the implementation of an evidence-based checklist for brain-dead potential organ donor management in intensive care units, a cluster randomised trialIntroductionThere is an increasing demand for multi-organ donors for organ transplantation programmes. This study protocol describes the Donation Network to Optimise Organ Recovery Study, a planned cluster randomised controlled trial that aims...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Cancer News -- ScienceDaily, Immunology: Not just supporting actors Non-classical monocytes...
 Cancer News -- ScienceDaily,Immunology: Not just supporting actorsNon-classical monocytes were long thought to play a purely surveillance role in the immune system. With the aid of a novel marker (PD-L1), researchers have now shown that they are directly involved in the regulation of immune response.Cancer News -- ScienceDaily43mSurvivors of childhood brain tumors experience lasting cognitive and socioeconomic burdensSurvivors of childhood brain tumors who received radiotherapy and were very young...
Αλέξανδρος Γ. Σφακιανάκης
1h
Bulletin of Experimental Biology and Medicine
Characteristics of Artificial Immunogens Containing Peptide Mimotopes of HIV-1 Epitopes Recognized by Monoclonal Antibodies 2F5 and 2G12The paper describes construction of TBI-based recombinant proteins TBI-2F5 and TBI-2G12 that contain peptide mimotopes of HIV-1 epitopes recognized by broadly neutralizing antibodies 2F5 and 2G12, respectively. The capacity of the immunogens to induce neutralizing antibodies was evaluated. The sera of BALB/c mice immunized with recombinant proteins TBI, TBI-2F5,...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cost-Effectiveness Analysis of Non-Statin Lipid-Modifying Agents for Secondary Cardiovascular Disease...
Cost-Effectiveness Analysis of Non-Statin Lipid-Modifying Agents for Secondary Cardiovascular Disease Prevention Among Statin-Treated Patients in ThailandAbstract Background Using non-statin lipid-modifying agents in combination with statin therapy provides additional benefits for cardiovascular disease (CVD) risk reduction, but their value for money has only been evaluated in high-income countries (HICs). Furthermore, studies mainly derive effectiveness data from a single trial or older meta-analyses....
Αλέξανδρος Γ. Σφακιανάκης
1h
Environmental+Science+and+Pollution+Research, Putative impacts of phytogenic additives to ameliorate...
Environmental+Science+and+Pollution+Research,Putative impacts of phytogenic additives to ameliorate lead toxicity in animal feedAbstract Lead (Pb) is a toxic heavy metal and an environmental pollutant, particularly because of its anthropogenic activity. The main impacts of Pb is recognized to cause injurious influences of various levels of the tropic chain, due to bio-accumulated lead causes many health issues such as intoxication of different body organs, such as kidneys and liver, and reproductive...
Αλέξανδρος Γ. Σφακιανάκης
1h
Nature Reviews Immunology, Middle management of CCR5 Nature Reviews Immunology, Published online:...
Nature Reviews Immunology,Middle management of CCR5Nature Reviews Immunology, Published online: 25 June 2019; doi:10.1038/s41577-019-0192-xLevels of CCR5 expression by CD4+ T cells, which influence the outcome of HIV-1 infection, are modulated by polymorphism of a non-coding RNA that affects mRNA stability.Nature Reviews Immunology - Issue - nature.com science feeds12h
Αλέξανδρος Γ. Σφακιανάκης
1h
 Neuro-Oncology - Advance Access, Hippocampus-avoidance in Pediatric Patients Neuro-Oncology...
 Neuro-Oncology - Advance Access,Hippocampus-avoidance in Pediatric PatientsNeuro-Oncology - Advance Access12h
Αλέξανδρος Γ. Σφακιανάκης
1h
Nature Reviews Genetics, A map of human individuality Nature Reviews Genetics, Published online:...
Nature Reviews Genetics,A map of human individualityNature Reviews Genetics, Published online: 25 June 2019; doi:10.1038/s41576-019-0149-8A study in Genome Biology reports an unbiased screen for human genomic regions at which interindividual variation in DNA methylation is consistent across cell types and tissues, providing new targets for studying epigenetic links to disease.Nature Reviews Genetics - Issue - nature.com science feeds11h
Αλέξανδρος Γ. Σφακιανάκης
1h
 International journal of basic and clinical endocrinology, Testosterone levels after treatment...
 International journal of basic and clinical endocrinology,Testosterone levels after treatment with urofollitropin in infertile patients with idiopathic mild reduction of testicular volumeAbstract Introduction A reduction of testicular volume (TV) represents an important clinical sign, which may hide sperm abnormalities and predispose to hypogonadism. Aim The primary purpose of this study was to evaluate the serum levels of total testosterone after treatment with urofollitropin in selected patients...
Αλέξανδρος Γ. Σφακιανάκης
1h
Drug Delivery and Translational Research, Anti-pollution cosmetic-based one-step formation of...
Drug Delivery and Translational Research,Anti-pollution cosmetic-based one-step formation of w/o/w multiple emulsion containing D-biotin for skin protection: fabrication and in vitro and in vivo evaluationAbstract Continuous contact of air pollutants on human skin has produced early ageing and led to roughness, dryness, poor elasticity, increased wrinkling and irregular pigmentation of the skin. The present study was carried out to fabricate an anti-pollution cosmetic-based w/o/w multiple emulsion...
Αλέξανδρος Γ. Σφακιανάκης
1h
Strahlentherapie und Onkologie, Stability and survival analysis of elderly patients with osteolytic...
Strahlentherapie und Onkologie,Stability and survival analysis of elderly patients with osteolytic spinal bone metastases after palliative radiotherapyAbstract Purpose This retrospective study aimed to evaluate the stability and fracture rates of osteolytic spinal bone metastases (SBM) in elderly patients following palliative radiotherapy (RT) and to derive prognostic factors for stability and survival. Methods A total of 322 patients aged at least 70 years received palliative RT at two major German...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cellular and Molecular Bioengineering, Shaft Function of Kinesin-1's α4 Helix in the Processive...
Cellular and Molecular Bioengineering,Shaft Function of Kinesin-1's α4 Helix in the Processive MovementAbstract Introduction Kinesin-1 motor is a molecular walking machine constructed with amino acids. The understanding of how those structural elements play their mechanical roles is the key to the understanding of kinesin-1 mechanism. Methods Using molecular dynamics simulations, we investigate the role of a helix structure, α4 (also called switch-II helix),...Latest Results for Cellular and Molecular...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Proceedings of the National Academy of Sciences, Correction for McKenzie et al., Caspase-1 inhibition...
 Proceedings of the National Academy of Sciences,Correction for McKenzie et al., Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis [Correction]NEUROSCIENCE Correction for "Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis," by Brienne A. McKenzie, Manmeet K. Mamik, Leina B. Saito, Roobina Boghozian, Maria Chiara Monaco, Eugene O. Major, Jian-Qiang Lu, William G. Branton, and Christopher...
Αλέξανδρος Γ. Σφακιανάκης
1h
Laser, High-resolution ultrasound for keloids and hypertrophic scar assessment Abstract Most...
Laser,High-resolution ultrasound for keloids and hypertrophic scar assessmentAbstract Most of the widely used scales to evaluate scars are subjective relying on clinical observations. There is a growing need to find out a noninvasive objective tool for this purpose. The study is aimed at evaluating the value of the high-resolution ultrasound in the assessment of the scars when compared with a clinical evaluation scoring system, the Vancouver Scar Scale (VSS). The study included 22 patients with hypertrophic...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cell and Tissue Banking, Effect of different cryopreservation regimens on Ehrlich carcinoma growth...
Cell and Tissue Banking,Effect of different cryopreservation regimens on Ehrlich carcinoma growthAbstract The freezing rate is a decisive factor in determining the purpose of using low temperatures, i.e., for cryoablation or cryobanking of tumor cells. The research aim was to determine effect of different cryopreservation regimens on Ehrlich carcinoma (EC) growth in vivo and subpopulation composition of the formed ascites. The previously cryopreserved with slow and rapid rates EC cells were cultured...
Αλέξανδρος Γ. Σφακιανάκης
1h
ChildrensMD, How to Manage Encopresis in Children Encopresis is a frustrating experience for...
ChildrensMD,How to Manage Encopresis in ChildrenEncopresis is a frustrating experience for children, parents, and teachers. Encopresis is generally defined as the passage of feces in inappropriate places, like underwear or the floor, by children who are past the age of toilet training. A variety of different factors can contribute to encopresis, including both physical and behavioral factors. This is why it is essential to involve both medical and behavioral health clinicians in the treatment of...
Αλέξανδρος Γ. Σφακιανάκης
1h
JoVE: Journal of Visualized Experiments, Measuring Relative Insulin Secretion using a Co-Secreted...
JoVE: Journal of Visualized Experiments,Measuring Relative Insulin Secretion using a Co-Secreted Luciferase SurrogateThis protocol describes how to perform rapid low-cost luciferase assays at medium-throughput using an insulin-linked Gaussia luciferase as a proxy for insulin secretion from beta cells. The assay can be performed with most luminescence plate readers and multichannel pipettes.JoVE: Journal of Visualized Experiments9hLexical Decision Task for Studying Written Word Recognition in Adults...
Αλέξανδρος Γ. Σφακιανάκης
1h
Maternal and Child Health Journal, The Demand and Supply Side Determinants of Access to Maternal,...
Maternal and Child Health Journal,The Demand and Supply Side Determinants of Access to Maternal, Newborn and Child Health Services in MalawiAbstract Objectives In order to improve maternal and neonatal outcomes, it is important to understand how to maximise the utilisation of MNCH services. The supply side (service-driven) factors affecting access to MNCH services are more commonly studied and are better understood than the demand side (community led) factors. The aim of this study was to identify...
Αλέξανδρος Γ. Σφακιανάκης
1h
Clinical Drug Investigation, Drug–Drug Interactions in Children and Adolescents Receiving Ledipasvir/Sofosbuvir...
Clinical Drug Investigation,Drug–Drug Interactions in Children and Adolescents Receiving Ledipasvir/Sofosbuvir for the Treatment of Hepatitis C Virus InfectionAbstract Background and Objective Drug–drug interactions need to be considered to optimize the pharmacotherapeutic outcome of direct-acting antivirals. The aim of this study was to report on possible drug–drug interactions between ledipasvir/sofosbuvir and other medications received by children and adolescents with hepatitis C virus, in addition...
Αλέξανδρος Γ. Σφακιανάκης
1h
CNS Drugs, Outcome Assessment in Trials of Pharmacological Treatments for Alcohol Use Disorders:...
CNS Drugs,Outcome Assessment in Trials of Pharmacological Treatments for Alcohol Use Disorders: Fair and Strict TestingAbstract Outcome assessment in the pharmacological treatment of alcohol use disorders (AUDs) faces specific challenges resulting from low adherence to treatment, high rates of dropout, and the susceptibility of patient self-reports to bias. This review discusses methodological issues in planning, conducting, and interpreting clinical trials on AUD treatment against the background...
Αλέξανδρος Γ. Σφακιανάκης
1h
EMCrit Blog - Emergency Department Critical Care, Tox and Hound – Fear and Loathing in Alcohol...
EMCrit Blog - Emergency Department Critical Care,Tox and Hound – Fear and Loathing in Alcohol Withdrawalby Jeff Lapoint "I was not proud of what I had learned, but I never doubted that it was worth knowing." Hunter S. Thompson I don't know why I've been identifying with the works of Hunter S Thompson of late. It's not because the political times seem eerily similar to that of 1972, nor because […] EMCrit Project by Tox & Hound.EMCrit Blog - Emergency Department Critical Care9h
Αλέξανδρος Γ. Σφακιανάκης
1h
 The Journal of Pediatrics, Discharge Instruction Comprehension and Adherence Errors: Interrelationship...
 The Journal of Pediatrics,Discharge Instruction Comprehension and Adherence Errors: Interrelationship Between Plan Complexity and Parent Health LiteracyTo examine associations between parent health literacy, discharge plan complexity, and parent comprehension of and adherence to inpatient discharge instructions.The Journal of Pediatrics9hCost-Savings of Fluoride Varnish Application in Primary Care for Medicaid-Enrolled Children in VirginiaTo determine the cost-benefit of fluoride varnish application...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Radiotherapy and Oncology, Clinical translation of FLASH radiotherapy: Why and how? Radiation...
 Radiotherapy and Oncology,Clinical translation of FLASH radiotherapy: Why and how?Radiation therapy (RT) is a major actor in cancer management, with more than half of all cancer patients treated with RT, mostly given with curative potential. RT generally exploits the empirical observation that normal tissues can recover from the harmful effects of ionizing radiation to a higher extent than tumors. This differential effect can be exacerbated by two factors that can independently increase the normal...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Journal of Clinical Neuroscience, Hemodynamic characteristics associated with thinner regions...
 Journal of Clinical Neuroscience,Hemodynamic characteristics associated with thinner regions of intracranial aneurysm wallCerebral aneurysm is a kind of devastating cerebrovascular disease characterized by pathological enlargement of local cerebral arteries [1,2]. Many risk factors have been demonstrated to be involved in the initiation and progression of cerebral aneurysms, but the exact pathophysiological mechanisms underlying aneurysm formation and rupture remain to be elucidated [3,4].Journal...
Αλέξανδρος Γ. Σφακιανάκης
1h
Journal of Stroke and Cerebrovascular Diseases, Paradoxical Cerebral Embolism as Initial Manifestation...
Journal of Stroke and Cerebrovascular Diseases,Paradoxical Cerebral Embolism as Initial Manifestation of Chronic Thromboembolic Pulmonary Hypertension: A Case ReportChronic thromboembolic pulmonary hypertension (CTEPH) is characterized by chronic thrombi in the pulmonary arteries, causing pulmonary hypertension and right heart failure. Early and accurate diagnosis are essential for successful treatment but are often difficult because clinical signs and symptoms can be nonspecific and risk factors,...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Oral & Maxillofacial Surgery, Knowledge, awareness, and perception of oral and maxillofacial...
 Oral & Maxillofacial Surgery,Knowledge, awareness, and perception of oral and maxillofacial surgery among the public and professionals in Saudi Arabia: a cross-sectional studyAlthough oral and maxillofacial surgery (OMS) is expanding rapidly in Saudi Arabia, accurate knowledge of the specialty appears to be lacking. The aim of this study was to assess the knowledge, awareness, and perception of OMS among the public and professionals in Saudi Arabia. A cross-sectional design was adopted, incorporating...
Αλέξανδρος Γ. Σφακιανάκης
1h
International Forum of Allergy & Rhinology, Predictive value of computed tomography in the...
International Forum of Allergy & Rhinology,Predictive value of computed tomography in the recurrence of chronic rhinosinusitis with nasal polypsBackground Chronic rhinosinusitis with nasal polyps (CRSwNP) is a nasal disease with a high tendency for recurrence. The aim of this study was to compare the use of computed tomography (CT) scan with other clinical parameters in predicting the recurrence of CRSwNP. Methods A total of 272 consecutive CRSwNP patients undergoing endoscopic functional sinus...
Αλέξανδρος Γ. Σφακιανάκης
1h
European Spine Journal, Morphological characteristics of the kangaroo lumbar intervertebral...
European Spine Journal,Morphological characteristics of the kangaroo lumbar intervertebral discs and comparison with other animal models used in spine researchAbstract Purpose Animal models are frequently used to elucidate pathomechanism and pathophysiology of various disorders of the human intervertebral disc (IVD) and also to develop therapeutic approaches. Here we report morphological characteristics of the kangaroo lumbar IVDs and compare them with other animal models used in spine research....
Αλέξανδρος Γ. Σφακιανάκης
1h
 Journal of Voice, Reliability and Validity of the Turkish Reflux Symptom Index To validate and...
 Journal of Voice,Reliability and Validity of the Turkish Reflux Symptom IndexTo validate and assess reliability of the Turkish Reflux Symptom Index (T-RSI).Journal of Voice8hReal-Time Acoustic Voice Analysis Using a Handheld Device Running Android Operating SystemWe developed a highly accessible acoustic voice analysis system (VArt) using a handheld device running Android operating system. To provide stable and reliable analysis using readily obtainable equipment under unfavorable conditions, we...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Annals of Allergy, Asthma & Immunology, Combination Biologic Therapy for Severe Persistent...
 Annals of Allergy, Asthma & Immunology,Combination Biologic Therapy for Severe Persistent AsthmaBiological pathways underlying severe asthma can be divided broadly into T2hi and T2low, with T2hi having a greater presence of type 2 innate lymphoid and helper T cells, the cytokines interleukin (IL)-4, IL-5, IL-13 and eosinophils, while T2low may show lack of inflammation or neutrophil predominance driven by Th1 and Th17 cells and the related cytokines IL-17 and interferon-γ.1-3 In the past few...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Digestive and Liver Disease, Duodenal focal lymphangiectasia A 58-year-old woman with a 6-month...
 Digestive and Liver Disease,Duodenal focal lymphangiectasiaA 58-year-old woman with a 6-month history of mild upper abdominal pain and fatigue was referred for esophagogastroduodenoscopy (EGD). Physical examination and laboratory tests were unremarkable. EGD revealed a local elevated finding suspicious for a subepithelial lesion in the second part of the duodenum. It measured approximately 2 cm in diameter. The surface pattern included small and white dots distributed among the duodenal villi (Fig....
Αλέξανδρος Γ. Σφακιανάκης
1h
Journal of Allergy and Clinical Immunology, TSLP epigenetically upregulates FcRγ-related receptors...
Journal of Allergy and Clinical Immunology,TSLP epigenetically upregulates FcRγ-related receptors on APCs and induces TH2/TH17 polarization via dectin-2TSLP upregulates FcRγ-related receptors on APCs through activation of pSTAT5, which recruits TET2 to induce FCER1G demethylation, and the TSLP-induced allergic TH2/TH17 polarization likely depends on the dectin-2-mediated allergen sensitization and upregulation in TH2/TH17-related cytokines.Journal of Allergy and Clinical Immunology7hRAGE-induced...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Plastic, Reconstructive & Aesthetic Surgery, One-step Facial Feminization Surgery: The importance...
 Plastic, Reconstructive & Aesthetic Surgery,One-step Facial Feminization Surgery: The importance of a custom made pre-operative planning and Patient Satisfaction Assessment.The availability of more accurate techniques used for transgender surgery, has resulted in an increased number of patients requesting facial feminization surgery (FFS). The aim of this study was to present authors male-to-female transsexual patients FFS pre-operative planning using photo-editing software, computer-aided design...
Αλέξανδρος Γ. Σφακιανάκης
1h
The neutrophil/lymphocyte ratio as a predictor of peritoneal metastasis during staging laparoscopy...
The neutrophil/lymphocyte ratio as a predictor of peritoneal metastasis during staging laparoscopy for advanced gastric cancer: a retrospective cohort analysis11hvia http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=12957&channel-name=World+Journal+of+Surgical+OncologyAbstractBackgroundThe use of staging laparoscopy (SL) has become widespread in patients with advanced gastric cancer (GC). This study aimed to evaluate the predictive value of the neutrophil/lymphocyte...
Αλέξανδρος Γ. Σφακιανάκης
1h
Giant villous adenoma of rectum- what is the malignant potential and what is the optimal treatment?...
Giant villous adenoma of rectum- what is the malignant potential and what is the optimal treatment? A case and review of literature7hvia http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=12957&channel-name=World+Journal+of+Surgical+OncologyAbstractIntroductionVillous adenomas are dubiously benign lesions, which are difficult to interpret because of their malignant potential. Distal villous adenomas present with bleeding or mucus discharge. Giant adenomas are...
Αλέξανδρος Γ. Σφακιανάκης
1h
Latest Plastic Surgery & Aesthetic Medicine Headlines, Clinicians at Stem Cell Clinics Often...
Latest Plastic Surgery & Aesthetic Medicine Headlines,Clinicians at Stem Cell Clinics Often Lack CredentialsResearchers found that many clinics offering unapproved stem cell interventions don't employ physicians trained to treat the conditions for which they advertise treatments. Medscape Medical NewsLatest Plastic Surgery & Aesthetic Medicine Headlines7h
Αλέξανδρος Γ. Σφακιανάκης
1h
PLOS ONE Alerts: New Articles, <i>In vitro</i> effects on calcium oxalate crystallization...
PLOS ONE Alerts: New Articles,<i>In vitro</i> effects on calcium oxalate crystallization kinetics and crystal morphology of an aqueous extract from <i>Ceterach officinarum</i>: Analysis of a potential antilithiatic mechanismby Roberta De Bellis, Maria Piera Piacentini, Maria Assunta Meli, Michele Mattioli, Michele Menotta, Michele Mari, Laura Valentini, Letizia Palomba, Donatella Desideri, Laura Chiarantini Ceterach officinarum Willd is a plant widespread throughout Europe...
Αλέξανδρος Γ. Σφακιανάκης
1h
NEJM Journal Watch: Physician's First Watch , USPSTF Recommends Interventions to Prevent Youth...
NEJM Journal Watch: Physician's First Watch ,USPSTF Recommends Interventions to Prevent Youth Smoking, Vaping; San Francisco Bans E-Cigarette SalesPrimary care clinicians should provide education or behavioral counseling to school-aged children and adolescents to help prevent them from starting to use tobacco products...NEJM Journal Watch: Physician's First Watch RSS Feed7hShorter Dual Antiplatelet Therapy May Be an Option for Patients Undergoing PCITwo JAMA studies suggest that a shorter duration...
Αλέξανδρος Γ. Σφακιανάκης
1h
Journal of Medical Case Reports - Latest Articles, Vitamin D treatment for chronic urticaria:...
Journal of Medical Case Reports - Latest Articles,Vitamin D treatment for chronic urticaria: a case reportChronic urticaria is characterized by recurrent hives, with or without angioedema, persisting for 6 weeks or longer. Although often suspected by patients, in fact specific allergen triggers are infrequent. In ...Journal of Medical Case Reports - Latest Articles6hAltered behavior with an organic cause: a case reportInsulinomas are pancreatic endocrine tumors of rare incidence worldwide, the vast...
Αλέξανδρος Γ. Σφακιανάκης
1h
CosmeticsDesign-Asia , Kao develops non-invasive RNA monitoring method after discovering its...
CosmeticsDesign-Asia ,Kao develops non-invasive RNA monitoring method after discovering its presence in sebumThe Bioscience Laboratory of Kao Corporation has claimed to have developed a new, non-invasive method of measuring human RNA after researchers discovered its presence in sebum.CosmeticsDesign-Asia RSS6h"For a better world": Amorepacific plots 2020 sustainability goals in newly published annual reportK-beauty conglomerate Amorepacific has published a new report detailing its sustainable practices...
Αλέξανδρος Γ. Σφακιανάκης
1h
The Lancet, [Correspondence] Zhang's guidelines vs WHO guidelines for diagnosing labour dystocia...
The Lancet,[Correspondence] Zhang's guidelines vs WHO guidelines for diagnosing labour dystocia – Authors' replyWe thank Annie Kroushev and her colleagues for their interest in our article that described our investigation of the effect of different labour progression guidelines.1The Lancet6h[Correspondence] Zhang's guidelines vs WHO guidelines for diagnosing labour dystociaIn their multicentre, cluster-randomised controlled trial, Stine Bernitz and colleagues1 found no significant difference in the...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Journal of the American Academy of Dermatology, Surgical Pearl: The Use of a Horizontal Mattress...
 Journal of the American Academy of Dermatology,Surgical Pearl: The Use of a Horizontal Mattress Suture and Notches in 3% Bismuth Tribromophenate-Impregnated Petrolatum Gauze Tie-Over Bolster Dressings to Improve Surgical Outcomes Following Skin GraftsJournal of the American Academy of Dermatology6h
Αλέξανδρος Γ. Σφακιανάκης
1h
The Lancet Oncology, [Comment] Anti-KIR3DL2 therapy in the treatment of Sézary syndrome In The...
The Lancet Oncology,[Comment] Anti-KIR3DL2 therapy in the treatment of Sézary syndromeIn The Lancet Oncology, Bagot and colleagues1 present the results of an international, multicentre, open-label, phase 1 study evaluating IPH4102 in patients with relapsed or refractory cutaneous T-cell lymphoma. IPH4102 is a humanised, first-in-class, monoclonal antibody that targets KIR3DL2, a cell surface protein widely expressed in cutaneous T-cell lymphoma, and predominantly in its leukaemic form, Sézary syndrome....
Αλέξανδρος Γ. Σφακιανάκης
1h
Journal of Nanoparticle Research, Comparison of biological markers in aerosol-weighed workplaces...
Journal of Nanoparticle Research,Comparison of biological markers in aerosol-weighed workplacesAbstract Airborne particulates present a potential hazard to health in a variety of indoor workplaces, from offices to the manufacturing floor. Dust and aerosols are two of the most common occupational risk factors in the workplace worldwide. It is very important to understand when it is sufficient to describe dust exposure only by given mass concentration that dust particles could be in the nanosized range...
Αλέξανδρος Γ. Σφακιανάκης
1h
Drugs.com - Daily MedNews, AHA News: Mom, Entrepreneur, Former NFL cheerleader – and Stroke...
Drugs.com - Daily MedNews,AHA News: Mom, Entrepreneur, Former NFL cheerleader – and Stroke Survivor at 39TUESDAY, June 25, 2019 (American Heart Association News) -- Growing up on a farm in northern Illinois, Cassie Perry participated in beauty pageants, joined the debate team and enjoyed competitive horseback riding. After college, she was a...Drugs.com - Daily MedNews5hChildhood Brain Tumor Survivors Face More StrugglesTUESDAY, June 25, 2019 -- Adult survivors of childhood brain tumors often face...
Αλέξανδρος Γ. Σφακιανάκης
1h
Water, Air, & Soil Pollution, Analysis of the Presence of Toxic Metals in Yerba Mate Samples:...
Water, Air, & Soil Pollution,Analysis of the Presence of Toxic Metals in Yerba Mate Samples: a Case Study from South BrazilAbstract The presence of toxic metals in soil enables them to be absorbed by plants. The RDC 42/2013 published by Brazilian Health Regulatory Agency (ANVISA) defines the maximum values of cadmium (0.4 mg kg−1) and lead (0.6 mg kg−1) in yerba mate commercialized in Common Market of the South (Mercosul). This work is a retrospective study that aimed to evaluate cadmium and...
Αλέξανδρος Γ. Σφακιανάκης
1h
EURASIP Journal on Advances in Signal Processing - Latest Articles, Realified L1-PCA for direction-of-arrival...
EURASIP Journal on Advances in Signal Processing - Latest Articles,Realified L1-PCA for direction-of-arrival estimation: theory and algorithmsSubspace-based direction-of-arrival (DoA) estimation commonly relies on the Principal-Component Analysis (PCA) of the sensor-array recorded snapshots. Therefore, it naturally inherits the sensitivity of PCA ag...EURASIP Journal on Advances in Signal Processing - Latest Articles5h
Αλέξανδρος Γ. Σφακιανάκης
1h
ACS Nano: Latest Articles (ACS Publications) [ASAP] A Flexible Microsupercapacitor with Integral...
ACS Nano: Latest Articles (ACS Publications)[ASAP] A Flexible Microsupercapacitor with Integral Photocatalytic Fuel Cell for Self-ChargingACS NanoDOI: 10.1021/acsnano.9b03603ACS Nano: Latest Articles (ACS Publications)4h[ASAP] Assembly Reactions of Hepatitis B Capsid Protein into Capsid Nanoparticles Follow a Narrow Path through a Complex Reaction LandscapeACS NanoDOI: 10.1021/acsnano.9b00648ACS Nano: Latest Articles (ACS Publications)4h[ASAP] Geometry-Based Self-Assembly of Histone–DNA Nanostructures...
Αλέξανδρος Γ. Σφακιανάκης
1h
Drugs.com - Pharma Industry News, Exposure to Anticholinergics May Increase Dementia Risk TUESDAY,...
Drugs.com - Pharma Industry News,Exposure to Anticholinergics May Increase Dementia RiskTUESDAY, June 25, 2019 -- Exposure to anticholinergic drugs is associated with an increased dementia risk, according to a study published online June 24 in JAMA Internal Medicine. Carol A.C. Coupland, Ph.D., from the University of Nottingham in the...Drugs.com - Pharma Industry News4hMortality Not Higher With Transfusions From Female DonorsTUESDAY, June 25, 2019 -- There is no increased risk for mortality among...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cancer Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes...
CancerNotch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicryBritish Journal of Cancer, Published online: 26 June 2019; doi:10.1038/s41416-019-0501-yNotch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicryCancer4hTargeting CXCL12/CXCR4 and myeloid cells to improve the therapeutic ratio in patient-derived cervical cancer models treated with radio-chemotherapyBritish...
Αλέξανδρος Γ. Σφακιανάκης
1h
BMC Neurology - Latest Articles ParkProTrain: an individualized, tablet-based physiotherapy training...
BMC Neurology - Latest ArticlesParkProTrain: an individualized, tablet-based physiotherapy training programme aimed at improving quality of life and participation restrictions in PD patients – a study protocol for a quasi-randomized, longitudinal and sequential multi-method studyParkinson's disease (PD) is one of the most common neurodegenerative diseases. Patients suffer from a variety of motor and non-motor symptoms that severely affect their daily lives and quality of life. In many...BMC Neurology...
Αλέξανδρος Γ. Σφακιανάκης
1h
Medicina oral, patología oral y cirugía bucal
pubmed: "med oral patol oral...Risk factors associated with the family care of people with serious mental illness.Related ArticlesRisk factors associated with the family care of people with serious mental illness. Med Oral Patol Oral Cir Bucal. 2019 Jun 24;: Authors: Carbonell Á, Navarro-Pérez JJ, Mestre MV Abstract BACKGROUND: The aim of the present study is to analyse the variables associated with the family care of people diagnosed with serious mental illness. MATERIAL AND METHODS: A cross-sectional...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cancer Education Systematic Review of Mammography Screening Educational Interventions for Hispanic...
Cancer EducationSystematic Review of Mammography Screening Educational Interventions for Hispanic Women in the United StatesAbstract In the United States (U.S.), Hispanics experience breast cancer disparities. Breast cancer is the leading cause of cancer-related death among Hispanic women, and Hispanic women receive mammography screening at lower rates than some other ethnic groups. This low rate of screening mammography is associated with increased risk for possible late-stage diagnosis and lower...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cancer Research Online First Articles Sphingosine-kinase-1 signaling promotes metastasis of triple-negative...
Cancer Research Online First ArticlesSphingosine-kinase-1 signaling promotes metastasis of triple-negative breast cancerTriple negative breast cancer (TNBC) is the most aggressive breast cancer subtype. To identify TNBC therapeutic targets, we performed integrative bioinformatics analysis of multiple breast cancer patient-derived gene expression datasets and focused on kinases with FDA-approved or in-pipeline inhibitors. Sphingosine kinase 1 (SPHK1) was identified as a top candidate. SPHK1 overexpression...
Αλέξανδρος Γ. Σφακιανάκης
1h
Molecular Cancer Research Online First Articles Cigarette Smoke Induces Metabolic Reprogramming...
Molecular Cancer Research Online First ArticlesCigarette Smoke Induces Metabolic Reprogramming of the Tumor Stroma in Head and Neck Squamous Cell CarcinomaAbstract: Head and neck squamous cell carcinoma (HNSCC) is comprised of metabolically linked distinct compartments. Cancer-associated fibroblasts (CAFs) and non-proliferative carcinoma cells display a glycolytic metabolism, whilst proliferative carcinoma cells rely on mitochondrial oxidative metabolism fueled by the catabolites provided by the...
Αλέξανδρος Γ. Σφακιανάκης
1h
G3: .Genes, Genomes, Genetics Mission - Online First Articles Genome-Wide Profiling of Polyadenylation...
G3: .Genes, Genomes, Genetics Mission - Online First ArticlesGenome-Wide Profiling of Polyadenylation Events in Maize Using High-Throughput Transcriptomic SequencesPolyadenylation is an essential post-transcriptional modification of eukaryotic transcripts that plays critical role in transcript stability, localization, transport, and translational efficiency. About 70% genes in plants contain alternative polyadenylation (APA) sites. Despite availability of vast amount of sequencing data, to date,...
Αλέξανδρος Γ. Σφακιανάκης
1h
Diagnostic Pathology - Latest Articles Validation of mitotic cell quantification via microscopy...
Diagnostic Pathology - Latest ArticlesValidation of mitotic cell quantification via microscopy and multiple whole-slide scannersThe establishment of whole-slide imaging (WSI) as a medical diagnostic device allows that pathologists may evaluate mitotic activity with this new technology. Furthermore, the image digitalization provides an ...Diagnostic Pathology - Latest Articles3hPrimary pseudomyogenic hemangioendothelioma of the vulva: a rare location for a rare entityPseudomyogenic hemangioendothelioma...
Αλέξανδρος Γ. Σφακιανάκης
1h
American Sleep & Breathing Academy Tradition of Excellence Continues at the Pro Bowl: ASBA...
American Sleep & Breathing AcademyTradition of Excellence Continues at the Pro Bowl: ASBA Diplomate Leads Sleep Apnea Screening For Former NFL PlayersORLANDO, FL – The actual National Football League (NFL) Pro Bowl game is famously uncompetitive. Instead of scoring touchdowns, the main goal among players is largely to stay uninjured.   Retired players who arrive for related festivities are also focusing on their health, but unlike their active gridiron colleagues, they face a variety of ailments....
Αλέξανδρος Γ. Σφακιανάκης
1h
Systematic Reviews - Latest Articles Protocol on a systematic review of qualitative studies on...
Systematic Reviews - Latest ArticlesProtocol on a systematic review of qualitative studies on asthma treatment challenges experienced in Sub-Saharan AfricaAsthma is a major worldwide public health problem affecting an estimated 334 million people with over 300,000 deaths annually. Twenty-two million disability-adjusted life years (DALYs) are lost annually due to...Systematic Reviews - Latest Articles3hEffectiveness and acceptability of methods of communicating the results of clinical research to...
Αλέξανδρος Γ. Σφακιανάκης
1h
RNA In Advance Telomeric small RNAs in the genus Caenorhabditis [Bioinformatics] Telomeric DNA...
RNA In AdvanceTelomeric small RNAs in the genus Caenorhabditis [Bioinformatics]Telomeric DNA is composed of simple tandem repeat sequences and has a G-rich strand that runs 5' to 3' towards the chromosome terminus. Small RNAs with homology to telomeres have been observed in several organisms and could originate from telomeres or from interstitial telomere sequences (ITSs), which are composites of degenerate and perfect telomere repeat sequences found on chromosome arms. We identified C. elegans small...
Αλέξανδρος Γ. Σφακιανάκης
1h
Spine - Featured Articles - Featured Articles Gadolinium Enhancement Is Not Associated With...
Spine - Featured Articles - Featured ArticlesGadolinium Enhancement Is Not Associated With Disc Inflammation in Patients With SciaticaStudy Design. Retrospective observational histological study. Objective. To evaluate the reliability of gadolinium enhancement as a marker for inflammation by associating gadolinium enhancement findings with the degree of inflammation as measured by macrophage infiltration in disc material retrieved during disc surgery in patients with sciatica. Summary of Background...
Αλέξανδρος Γ. Σφακιανάκης
1h
RSC - Chem. Commun. latest articles Cu-catalyzed highly selective reductive functionalization...
RSC - Chem. Commun. latest articlesCu-catalyzed highly selective reductive functionalization of 1,3-diene using H2O as stoichiometric hydrogen atom donorChem. Commun., 2019, Accepted ManuscriptDOI: 10.1039/C9CC04011K, CommunicationQifan Li, Xiaoyang Jiao, Mimi Xing, Penglin Zhang, Qian Zhao, Chun ZhangA copper-catalyzed highly regio- and diastereo-selective reductive reaction of terminal 1,3-diene with water and aldehyde have been developed. This chemistry afforded the terminal alkenyl group containing...
Αλέξανδρος Γ. Σφακιανάκης
1h
Clinical Cancer Research Online First Articles Nivolumab in Patients With Recurrent or Metastatic...
Clinical Cancer Research Online First ArticlesNivolumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: Efficacy and Safety in CheckMate 141 by Prior Cetuximab UsePurpose: Cetuximab, which modulates immune responses, may affect the efficacy of subsequent immunotherapy. Here, we assessed outcomes with nivolumab, by prior cetuximab exposure, in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) who had experienced...
Αλέξανδρος Γ. Σφακιανάκης
1h
Sleep and Breathing The association of OSAS and uvula: the role of MRI in this egg-chicken problem...
Sleep and BreathingThe association of OSAS and uvula: the role of MRI in this egg-chicken problem in OSASAbstract Purpose Obstructive sleep apnea syndrome (OSAS) is a condition resulting from repetitive partial or complete upper airway obstruction, and its etiology remains uncertain. Polysomnography is the gold standard diagnostic test for OSAS. However, there are long wait times for this evaluation, so questionnaires or ancillary diagnostic methods are used to select appropriate patients. One of...
Αλέξανδρος Γ. Σφακιανάκης
1h
Transparency in Decision Modelling: What, Why, Who and How? 1h via http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=40273&channel-name=PharmacoEconomics...
Transparency in Decision Modelling: What, Why, Who and How?1hvia http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=40273&channel-name=PharmacoEconomicsAbstractTransparency in decision modelling is an evolving concept. Recently, discussion has moved from reporting standards to open-source implementation of decision analytic models. However, in the debate about the supposed advantages and disadvantages of greater transparency, there is a lack of definition. The...
Αλέξανδρος Γ. Σφακιανάκης
1h
Investigational New Drugs A randomized phase 2 trial of the efficacy and safety of a novel topical...
Investigational New DrugsA randomized phase 2 trial of the efficacy and safety of a novel topical povidone-iodine formulation for Cancer therapy-associated ParonychiaSummary Purpose Cancer therapy-associated paronychia (CAP) is a frequent adverse event associated with cytotoxic and targeted therapies that may impact dosing of anticancer therapies and patient quality of life (QoL). There are currently no evidence-based management strategies or approved treatments for CAP. Materials and Methods This...
Αλέξανδρος Γ. Σφακιανάκης
1h
BMC Infectious Diseases - Latest Articles Frequency of the Mycobacterium tuberculosis RDRio genotype...
BMC Infectious Diseases - Latest ArticlesFrequency of the Mycobacterium tuberculosis RDRio genotype and its association with multidrug-resistant tuberculosisIn recent decades, Mycobacterium tuberculosis with the RDRio genotype, frequently isolated from tuberculosis patients in Rio de Janeiro, has become part of the Latin American – Mediterranean (LAM) family and has ...BMC Infectious Diseases - Latest Articles1hClusterization of co-morbidities and multi-morbidities among persons living with HIV:...
Αλέξανδρος Γ. Σφακιανάκης
1h
Stem Cells and Development - Table of Contents Acid-Sensitive Ion Channels Are Expressed in Human...
Stem Cells and Development - Table of ContentsAcid-Sensitive Ion Channels Are Expressed in Human Induced Pluripotent Stem Cell-Derived CardiomyocytesStem Cells and Development, Ahead of Print.Stem Cells and Development - Table of Contents1hDifferential Immunomodulatory Effects of Human Bone Marrow-Derived Mesenchymal Stromal Cells on Natural Killer CellsStem Cells and Development, Ahead of Print.Stem Cells and Development - Table of Contents13h
Αλέξανδρος Γ. Σφακιανάκης
1h
Self-administered acupressure for allergic rhinitis: study protocol for a randomized, single-blind,...
Self-administered acupressure for allergic rhinitis: study protocol for a randomized, single-blind, non-specific controlled, parallel trial1hby Yaqun Liang, George Binh Lenon and Angela Wei Hong Yang via Trials - Latest ArticlesAllergic rhinitis (AR) is an IgE-mediated inflammatory disease. Current conventional therapies for AR are unsatisfactory. Acupuncture has been recommended as an optional treatment for AR patients who are inter...
Αλέξανδρος Γ. Σφακιανάκης
1h
International Journal of Molecular Sciences IJMS, Vol. 20, Pages 3113: Immortalized Human hTert/KER-CT...
International Journal of Molecular SciencesIJMS, Vol. 20, Pages 3113: Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus VulgarisIJMS, Vol. 20, Pages 3113: Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris International Journal of Molecular Sciences doi: 10.3390/ijms20133113 Authors: Benedikt Beckert Francesca Panico Robert Pollmann Rüdiger...
Αλέξανδρος Γ. Σφακιανάκης
1h
BMJ Case Reports Last 6 Issues Multiple sites acquired lipodystrophy in two siblings: a rare...
BMJ Case Reports Last 6 IssuesMultiple sites acquired lipodystrophy in two siblings: a rare adverse effect of intramuscular triamcinoloneBMJ Case Reports Last 6 Issues45mRare case of Bing-Neel syndrome treated successfully with ibrutinibWaldenstrom's macroglobulinaemia (WM) is a lymphoproliferative disorder of the B cell origin. It is characterised by the presence of IgM paraprotein in the serum and lymphoplasmacytic lymphoma cells in the bone marrow with extranodal involvement relatively uncommon....
Αλέξανδρος Γ. Σφακιανάκης
1h
Use of Ceftazidime-Avibactam in Infants and Children Ceftazidime-avibactam is now approved for the...
Use of Ceftazidime-Avibactam in Infants and ChildrenCeftazidime-avibactam is now approved for the treatment of gram-negative bacterial infections in pediatric patients. Find out what there is to know. Pediatric PharmacotherapyMedscape Allergy & Clinical Immunology Headlines35m
Αλέξανδρος Γ. Σφακιανάκης
1h
Environmental+Science+and+Pollution+Research Energy reserves and respiration rate in the earthworm...
Environmental+Science+and+Pollution+ResearchEnergy reserves and respiration rate in the earthworm Eisenia andrei after exposure to zinc in nanoparticle or ionic formAbstract The energy budget is an indicator of an organism's overall condition. Changes in energy reserves and/or energy consumption have been used as biomarkers of toxic stress. To understand the effects of different forms and concentrations of Zn and the costs of effective Zn regulation by the earthworm Eisenia andrei, we performed a...
Αλέξανδρος Γ. Σφακιανάκης
1h
MedicineNet Cancer General Making Sense of Mammography Guidelines Title: Making Sense of Mammography...
MedicineNet Cancer GeneralMaking Sense of Mammography GuidelinesTitle: Making Sense of Mammography GuidelinesCategory: Health NewsCreated: 6/25/2019 12:00:00 AMLast Editorial Review: 6/25/2019 12:00:00 AMMedicineNet Cancer General29mCould 3-D Mammograms Soon Be the Standard for Breast Cancer Screening?Title: Could 3-D Mammograms Soon Be the Standard for Breast Cancer Screening?Category: Health NewsCreated: 6/24/2019 12:00:00 AMLast Editorial Review: 6/25/2019 12:00:00 AMMedicineNet Cancer General29m
Αλέξανδρος Γ. Σφακιανάκης
1h
Future Oncology Anti-PD-1 versus anti-PD-L1 therapy in patients with pretreated advanced non-small-cell...
Future OncologyAnti-PD-1 versus anti-PD-L1 therapy in patients with pretreated advanced non-small-cell lung cancer: a meta-analysisFuture Oncology, Ahead of Print.Future Oncology23mExcess of second tumors in denosumab-treated patients: a metabolic hypothesisFuture Oncology, Ahead of Print.Future Oncology23mPrognostic impact of tumor-associated macrophage infiltration in esophageal cancer: a meta-analysisFuture Oncology, Ahead of Print.Future Oncology23mPreoperative high c-reactive protein/albumin...
Αλέξανδρος Γ. Σφακιανάκης
1h
 BMJ Open recent issues DONORS (Donation Network to Optimise Organ Recovery Study): Study protocol...
 BMJ Open recent issuesDONORS (Donation Network to Optimise Organ Recovery Study): Study protocol to evaluate the implementation of an evidence-based checklist for brain-dead potential organ donor management in intensive care units, a cluster randomised trialIntroductionThere is an increasing demand for multi-organ donors for organ transplantation programmes. This study protocol describes the Donation Network to Optimise Organ Recovery Study, a planned cluster randomised controlled trial that aims...
Αλέξανδρος Γ. Σφακιανάκης
1h
Family Violence
Coexistence of Intimate Partner Violence and Child Maltreatment among Adolescents in KosovoAbstractHigh levels of domestic and intimate partner violence are continuously reported in Kosovo, and child maltreatment by parents is common. This study explores the coexistence of intimate partner violence and child maltreatment and its association with sociodemographic factors. A sample of 208 Kosovar adolescents was assessed using the Conflict Tactic Scale and the Parent-Child Conflict Tactic Scale. The...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cellular and Molecular Life Sciences
Helicobacter pylori infection and gastrointestinal tract cancer biology: considering a double-edged sword reflectionAdult stem cells at work: regenerating skeletal muscleAbstractSkeletal muscle regeneration is a finely tuned process involving the activation of various cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are indispensable for skeletal muscle regeneration. Their functionality is critically modulated by intrinsic signaling pathways as well as by interactions...
Αλέξανδρος Γ. Σφακιανάκης
1h

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174,00302841026182,alsfakia@gmail.com

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