Metastatic malignant struma ovarii: a case report and review of the literature on the management of malignant struma ovarii

xlomafota13 shared this article with you from Inoreader Metastatic malignant struma ovarii: a case report and review of the literature on the management of malignant struma ovarii Via radioactive iodine Acta Clin Belg. 2021 Jun 30:1-5. doi: 10.1080/17843286.2021.1944583. Online ahead of print. ABSTRACT OBJECTIVES: To present a case of metastatic struma ovarii, to review the literature on malignant struma ovarii and to discuss the management in locoregional and metastatic disease. METHODS: We present a case of an 82-year-old patient with a malignant struma ovarii and liver metastasis. The patient was treated with pelvic surgery, total thyroidectomy, radioactive iodine therapy and TSH suppression therapy with levothyroxine. We performed a PubMed search for case reports of metastatic struma ovarii. RESULTS: 43 cases of metastatic struma ovarii were identified. 53.5% of patients presented with metastatic disease at diagnosis. Mean time to development of metastasis was 6.9 years in the group with initial locoregional disease. First-line treatment was pelvic surgery in all patients. Thyroidectomy was performed in 83.7% of patients, subsequent radioactive iodine therapy in 79.1%, followed by TSH suppression therapy in 46.5% of patients. Mean time of follow-up after diagnosis of metastases was 3.6 years, ranging from 0.5 to 24 years. At the end of the follow-up, 51.1% of patients were free of disease, 34.9% were alive with disease, 7.0% died of disease and 7.0% were lost to follow-up. CONCLUSION: The majority of patients with metastatic struma ovarii were treated with pelvic surgery, total thyroidectomy and radioactive iodine therapy. Suppression o f TSH with levothyroxine was given in less than half of the patients. In non-metastatic setting, the same approach could be considered depending on the patient profile. PMID:34191687 | DOI:10.1080/17843286.2021.1944583 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Isolated Traumatic Dislocation of the Malleus into the External Auditory Canal

xlomafota13 shared this article with you from Inoreader Isolated Traumatic Dislocation of the Malleus into the External Auditory Canal Via ear nose throat Ear Nose Throat J. 2021 Jun 30:1455613211026529. doi: 10.1177/01455613211026529. Online ahead of print. ABSTRACT We report a rare case of isolated malleus dislocation into the external auditory canal with lateralized intact tympanic membrane following a head trauma. The patient was a 63-year-old woman who presented at the outpatient department of our institute with hearing loss of 10 years' duration after a bicycle accident. During physical examination of the patient, total d islocation of the malleus-like bony structure into the external auditory canal on the right side was observed. In the computed tomography scan, an isolated malleus dislocation with intact incus-stapes articulation was identified. The patient was successfully treated with endoscopic exploratory tympanotomy and partial ossicular replacement prosthesis. The isolated malleus dislocation can rarely occur after trauma. A careful diagnostic step through history, physical examination, and temporal bone computed tomography scan are needed to confirm this rare condition. PMID:34191618 | DOI:10.1177/0 1455613211026529 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Endoscopic Endonasal Orbital Apex Decompression for Carotid Cavernous Fistula

xlomafota13 shared this article with you from Inoreader Endoscopic Endonasal Orbital Apex Decompression for Carotid Cavernous Fistula Via ear nose throat Ear Nose Throat J. 2021 Jun 30:1455613211030347. doi: 10.1177/01455613211030347. Online ahead of print. ABSTRACT SIGNIFICANCE STATEMENT: This case report demonstrates a novel approach to treating a rare indirect carotid cavernous fistula (CCF) and associated abducens palsy. Although endovascular treatment is the standard of care in the management of CCFs, it was contraindicated in this patient. Instead, she underwent an endoscopic endonasal approach (EEA) with decompression of the medial orbital apex, including the cavernous sinus and optic nerve, with complete resolution of headache, lateral gaze palsy, and diplopia within 2 months. PMID:34191645 | DOI:10.1177/01455613211030347 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Manejo quirúrgico de cáncer papilar de tiroides con invasión traqueal: Reporte de dos casos en Servicio de Otorrinolaringología de Hospital Carlos Van Buren

xlomafota13 shared this article with you from Inoreader Manejo quirúrgico de cáncer papilar de tiroides con invasión traqueal: Reporte de dos casos en Servicio de Otorrinolaringología de Hospital Carlos Van Buren Via Otorrinolaringología y cirugía de cabeza y cuello Resumen La invasión traqueal corresponde al tercer sitio más común de extensión extratiroidea del cáncer de tiroides. Se debe sospechar en caso de disnea, disfonía, estridor y hemoptisis, sin embargo, hasta un 30% de los pacientes se pueden presentar de forma asintomática, pesquisándose al momento de la cirugía. La nasofibroscopía de rutina, una alta sospecha y una planificación quirúrgica adecuada, serán fundamentales para lograr una resección tumoral completa y mejorar tanto el pronóstico como el control local. A continuación, presentamos dos casos clínicos manejados con resección cricotraqueal con anastomosis términoterminal en el Servicio de Otorrinolaringología del Hospital Carlos Van Buren. Abstract Tracheal invasion is the third most common site of extrathyroideal invasión of thyroid cancer, recognized as a por prognostic indicator. It should be suspected in case of dyspnea, dysphonia, stridor, and hemoptysis. However, up to 30% of cases are asymp tomatic, detected at the time of surgery. Routine nasofibroscopy, thorough examination and surgical planning are essential to ensure a complete tumoral resection, improvement in prognostic and local control of disease. We present two cases with cricotracheal resection and end-to-end anastomosis in Otholaringology Service from the Carlos Van Buren Hospital. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Tumor maligno de la vaina nerviosa periférica del nervio vago: Reporte de un caso

xlomafota13 shared this article with you from Inoreader Tumor maligno de la vaina nerviosa periférica del nervio vago: Reporte de un caso Via Otorrinolaringología y cirugía de cabeza y cuello Resumen Los tumores malignos de la vaina nerviosa forman parte del 5% de los sarcomas de partes blandas. Si bien son infrecuentes, su incidencia aumenta en caso de neurofibromatosis tipo 1. Cuando estos tumores están ubicados en cabeza y cuello, suelen ser asintomáticos, por lo que su diagnóstico es tardío. El tratamiento es principalmente quirúrgico, con una tasa de recidiva importante y pobre sobrevida a los 5 años. Se presenta el reporte de un caso de una paciente de 52 años con antecedentes de neurofibromatosis tipo 1 y un tumor maligno de vaina nerviosa periférica del nervio vago, localizado en el espacio parafaríngeo. Abstract Malignant peripheral nerve sheath tumors are part of 5% of soft tissue sarcomas. Although they are infrequent, their incidence increases in case of neurofibromatosis type 1. When these tumors are located in the head and neck, they are usually asymptomatic, so their diagnosis is delayed. Treatment is primarily surgical, with a significant recurrence rate and poor 5-year survival. We present a case report of a 52-year-old patient with a history of type 1 neurofibromatosis and a malignant peripheral nerve sheath tumor of the vagus, located in the parapharyngeal space. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Desafío diagnóstico y terapéutico de carcinoma mucoepidermoide palatino: reporte de un caso

xlomafota13 shared this article with you from Inoreader Desafío diagnóstico y terapéutico de carcinoma mucoepidermoide palatino: reporte de un caso Via Otorrinolaringología y cirugía de cabeza y cuello Resumen Las neoplasias en glándulas salivales son infrecuentes, representando menos del 3% de los tumores de cabeza y cuello. El carcinoma mucoepidermoide es el tumor maligno más común en glándulas salivales, siendo su principal ubicación la parótida. Clínicamente se asemeja a otras lesiones de mucosa oral, por lo cual, es importante realizar un correcto diagnóstico diferencial. Su comportamiento biológico se relaciona con el grado histológico tumoral, factor relevante en el pronóstico y tratamiento de esta neoplasia. Presentamos el caso de un paciente hombre de 75 años afectado con un tumor en paladar con diagnóstico de carcinoma mucoepidermoide de bajo grado. Como tratamiento se realizó una maxilectomía parcial y una placa obturadora en base a una prótesis removible y posterior reconstrucción con un colgajo libre microvascularizado. Actualmente el paciente se encuentra en controles periódicos, libre de enfermedad. Los tumores de glándulas salivales son un d esafío diagnóstico, requieren de exámenes imagenológicos y del estudio histopatológico. Cuando existen dudas en el diagnóstico, se debe considerar repetir la toma de la muestra o la obtención de biopsias de más de una zona representativa que permita el diagnóstico de la lesión. Abstract Salivary gland neoplasms are infrequent lesions representing less than 3% of head and neck tumors. Mucoepidermoid carcinoma is the most common malignant tumor in salivary glands, being the parotid the most usual location. Clinically, it resembles other oral mucosa lesions, therefore, it is important to make a correct differential diagnosis. Its biological behavior is related to the tumor histological grade, a relevant factor in the prognosis and treatment of this neoplasm. We reported a case of a 75-year-old-man, with a tumor in the palate, diagnosed as low-grade mucoepidermoid carcinoma. A partial maxillectomy and an obturator plate were performed based on a removable prosthesis and sub sequent reconstruction with a microvascularized free flap. The patient is currently undergoing regular checkups, maintaining disease free. Salivary gland tumors are a diagnostic challenge, requiring imaging tests and histopathological study. In case of doubts with the diagnosis, it should be considered to biopsy more than area or to repeat the biopsy in order to obtain a representative sample that allows the diagnosis of the lesion. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Angiomiolipoma nasal: reporte de dos casos y revisión de la literatura

xlomafota13 shared this article with you from Inoreader Angiomiolipoma nasal: reporte de dos casos y revisión de la literatura Via Otorrinolaringología y cirugía de cabeza y cuello Resumen El angiomiolipoma es una lesión hamartomatosa, habitualmente de localización renal asociado a esclerosis tuberosa. La ubicación nasosinusal es extremadamente infrecuente y se puede presentar con obstrucción nasal y epistaxis. Se presentan dos casos de angiomiolipoma de cavidad nasal diagnosticados en el Hospital Carlos Van Buren de Valparaíso. Ambos casos se presentaron como masa nasal unilateral, se estudiaron con tomografía computada y fueron tratados con biopsia escisional, sin presentar recidivas durante su seguimiento. El anigiomiolipoma está compuesto por vasos sanguíneos, músculo liso y adipocitos. Existen diferencias entre el angiomiolipoma del riñón versus el de piel, cavidad oral y nasal (angiomiolipomas mucocutáneos); estos últimos son extremadamente infrecuentes, de menor tamaño, con presencia de agregados linfoides, negativos para antígeno específico de melanoma HMB-45 y sin asociación a esclerosis tuberosa. Existen pocos casos reportados e n la literatura de esta patología, por lo que existe poca evidencia. Clínicamente, se presentan con obstrucción nasal, epistaxis recurrente, sensación de masa nasal. El estudio preoperatorio depende de su extensión y puede incluir una tomografía computada y/o angiografía para identificar su irrigación. El diagnóstico definitivo es anatomopatológico. Si se logra la escisión completa, no se han reportado recidivas, por lo que presenta un excelente pronóstico. Abstract Angiomyolipoma is a hamartomatous lesion, usually of a renal location associated with tuberous sclerosis. Nasosinusal location is extremely rare and can present with nasal obstruction and epistaxis. Two cases of angiomyolipoma of the nasal cavity diagnosed at the Carlos Van Buren Hospital in Valparaíso are presented. Both cases presented as a unilateral nasal mass, and were studied with computed tomography, and treated with an excisional biopsy, with no recurrences during follow-up. Anigiomyolipoma is com posed of blood vessels, smooth muscle and adipocytes. There are differences between angiomyolipoma of the kidney versus skin, oral and nasal cavity (mucocutaneous angiomyolipomas). The latter are extremely infrequent, smaller in size, with the presence of lymphoid aggregates, negative for the HMB-45 specific melanoma antigen and without association with tuberous sclerosis. There are few cases reported in the literature of this pathology, so there is little evidence. Clinically, they present with nasal obstruction, recurrent epistaxis, sensation of nasal mass. The preoperative study depends on its extension and may include a computed tomography and/or angiography to identify its irrigation. The definitive diagnosis is pathological. If complete excision is achieved, no recurrences have been reported, so it has an excellent prognosis. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.